Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.32 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26050634 | 0.89 | MAOA (0.43) | MAOAMCHR1ERCC1ERCC4 | |
| SCHEMBL26051600 | 0.82 | EPHX2 (0.36) | EPHX2HPGDEPHX1MTORTRPV1 | |
| SCHEMBL26052061 | 0.82 | EPHX2 (0.36) | EPHX2HPGDEPHX1MTORTRPV1 | |
| SCHEMBL26052060 | 0.80 | ROCK2 (0.43) | EPHX2KMT2AKCNH2 | |
| SCHEMBL26051696 | 0.79 | SMN1; SMN2 (0.38) | MEN1LMNAKMT2AMCHR1 | |
| SCHEMBL26052184 | 0.79 | SMN1; SMN2 (0.38) | MEN1LMNAKMT2AMCHR1 | |
| SCHEMBL25374463 | 0.78 | EPHX2 (0.39) | EPHX2CYP2C9PTPN1MTORMEN1 | |
| SCHEMBL30580171 | 0.78 | EPHX2 (0.39) | EPHX2CYP2C9PTPN1MTORMEN1 | |
| SCHEMBL26051934 | 0.73 | ERCC1 (0.46) | MAOAMCHR1ERCC1ERCC4 | |
| SCHEMBL29564250 | 0.72 | PTPN1 (0.46) | EPHX2CYP2C9PTPN1HPGDMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023158584-A1 | NEW BICYCLOPENTANE DERIVATIVES | ICAGEN, LLC (US) | 2023-08-24 | — | — | WO | disclosed |