Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.55 |
| ▸ | HTR1D | P28221 | 4/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.49 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.49 |
| ▸ | PGR | P06401 | 3/20 | 0.49 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 3/20 | 0.48 |
| ▸ | HTR1B | P28222 | 3/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | HTR2B | P41595 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19067627 | 0.84 | HTR2A (0.61) | HTR2AHTR1DMTNR1AMTNR1BNR3C1 | |
| SCHEMBL25397483 | 0.84 | HTR2A (0.69) | HTR2ANR3C1HTR2CHTR1ASLC6A4 | |
| SCHEMBL30457763 | 0.84 | HTR2A (0.69) | HTR2ANR3C1HTR2CHTR1ASLC6A4 | |
| SCHEMBL29280789 | 0.82 | HTR2A (0.49) | HTR2AHTR1DMTNR1AMTNR1BNR3C1 | |
| SCHEMBL699380 | 0.81 | HTR2A (0.58) | HTR2AHTR1DMTNR1AMTNR1BNR3C1 | |
| SCHEMBL30811419 | 0.81 | HTR2A (0.70) | HTR2AHTR1DHTR2CHTR1BHTR1A | |
| SCHEMBL1120488 | 0.81 | HTR2A (0.70) | HTR2AHTR1DHTR2CHTR1BHTR1A | |
| SCHEMBL24913231 | 0.81 | HTR2A (0.70) | HTR2AHTR1DHTR2CHTR1BHTR1A | |
| SCHEMBL19847298 | 0.81 | HTR2A (0.71) | HTR2AHTR1DMTNR1AMTNR1BHTR2C | |
| SCHEMBL29633157 | 0.81 | HTR2A (0.71) | HTR2AHTR1DMTNR1AMTNR1BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230355583-A1 | METHODS FOR DELIVERY OF PSYCHEDELIC MEDICATIONS BY INHALATION AND SYSTEMS FOR PERFORMING THE METHODS | CYBIN IRL LIMITED (IE) | 2023-11-09 | — | — | US | disclosed |
| US-20230357147-A1 | DEUTERATED TRYPTAMINE DERIVATIVES AND METHODS OF USE | CYBIN IRL LIMITED (IE) | 2023-11-09 | — | — | US | disclosed |
| US-11746088-B2 | Deuterated tryptamine derivatives and methods of use | CYBIN IRL LIMITED (IE) | 2023-09-05 | — | — | US | disclosed |
| US-11724985-B2 | Deuterated tryptamine derivatives and methods of use | CYBIN IRL LIMITED (IE) | 2023-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357147-A1 | DEUTERATED TRYPTAMINE DERIVATIVES AND METHODS OF USE | TPH2, HTR2C, TPH1 | HTR2A 4/4885HTR1D 18/4885MTNR1A 54/4885 |
| US-11746088-B2 | Deuterated tryptamine derivatives and methods of use | TPH2, HTR2C, TPH1 | HTR2A 4/4885HTR1D 18/4885MTNR1A 54/4885 |
| US-11724985-B2 | Deuterated tryptamine derivatives and methods of use | TPH2, HTR2C, TPH1 | HTR2A 4/4885HTR1D 18/4885MTNR1A 54/4885 |
| US-20230355583-A1 | METHODS FOR DELIVERY OF PSYCHEDELIC MEDICATIONS BY INHALATION AND SYSTEMS FOR PERFORMING THE METHODS | PNMT, CNR2, CNR1 | HTR2A 9/4885HTR1D 36/4885MTNR1A 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.