Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 4/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23682724 | 0.90 | KDM4E (0.49) | KDM4EALDH1A1MAPK1L3MBTL1CYP2C19 | |
| SCHEMBL25736544 | 0.82 | NR4A1 (0.48) | KDM4EALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL7717844 | 0.79 | CYP1A2 (0.59) | CYP1A2CNR2CNR1CYP2A6CYP3A4 | |
| SCHEMBL23815802 | 0.78 | ALDH1A1 (0.41) | CYP1A2KDM4EALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL669648 | 0.78 | CYP1A2 (0.56) | CYP1A2KDM4EALDH1A1CNR2CNR1 | |
| SCHEMBL31347531 | 0.78 | CYP1A2 (0.56) | CYP1A2KDM4EALDH1A1CNR2CNR1 | |
| SCHEMBL7829452 | 0.78 | CYP1A2 (0.56) | CYP1A2ALDH1A1CNR2CNR1CYP2A6 | |
| SCHEMBL405225 | 0.78 | CYP1A2 (0.56) | CYP1A2KDM4EALDH1A1CNR2CNR1 | |
| SCHEMBL6914124 | 0.76 | CYP1A2 (0.54) | CYP1A2KDM4EALDH1A1CNR2CNR1 | |
| SCHEMBL601658 | 0.76 | CYP1A2 (0.54) | CYP1A2ALDH1A1CNR2CNR1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11731967-B2 | Inhibitors of TRIM33 and methods of use | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11731967-B2 | Inhibitors of TRIM33 and methods of use | TRIM33, TRIM28, TRIM4 | CYP1A2 3341/4885KDM4E 1284/4885ALDH1A1 3246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.