Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 1/20 | 0.32 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | TPH1 | P17752 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31596183 | 1.00 | UBE2M (0.32) | UBE2MDCUN1D1AOC3TPH1HSD11B1 | |
| SCHEMBL26053991 | 0.87 | GRM5 (0.34) | UBE2MDCUN1D1AOC3TPH1HSD11B1 | |
| SCHEMBL26053711 | 0.87 | TPH1 (0.41) | UBE2MDCUN1D1AOC3TPH1 | |
| SCHEMBL26055260 | 0.87 | AOC3 (0.33) | UBE2MDCUN1D1AOC3TPH1HSD11B1 | |
| SCHEMBL26054970 | 0.87 | RAB9A (0.33) | UBE2MDCUN1D1AOC3TPH1 | |
| SCHEMBL26054888 | 0.87 | AOC3 (0.33) | UBE2MDCUN1D1AOC3TPH1HSD11B1 | |
| SCHEMBL31596204 | 0.85 | GRM5 (0.36) | UBE2MDCUN1D1AOC3TPH1HSD11B1 | |
| SCHEMBL26055111 | 0.83 | UBE2M (0.35) | UBE2MDCUN1D1AOC3TPH1 | |
| SCHEMBL31595722 | 0.83 | UBE2M (0.35) | UBE2MDCUN1D1AOC3TPH1 | |
| SCHEMBL26054886 | 0.83 | UBE2M (0.35) | UBE2MDCUN1D1AOC3TPH1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164237-A1 | COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS | AGIOS PHARMACEUTICALS, INC. (US) | 2023-08-31 | — | — | WO | disclosed |