SCHEMBL260557

SCHEMBL260557

CC(C)C(=O)CCCCCCCCCCCN

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 4/20 0.56
LMNA P02545 2/20 0.52
THRB P10828 2/20 0.52
KMT2A Q03164 2/20 0.52
MEN1 O00255 1/20 0.52
ALDH1A1 P00352 1/20 0.52
PLG P00747 1/20 0.52
ALOX15 P16050 1/20 0.52
SLC6A2 P23975 1/20 0.52
RECQL P46063 1/20 0.52
SLC6A3 Q01959 1/20 0.52
CYP2D6 P10635 1/20 0.48
NFKB1 P19838 1/20 0.48
BLM P54132 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
CES2 O00748 1/20 0.40
LTA4H P09960 1/20 0.39
GABRR3 A8MPY1 1/20 0.39
GABRP O00591 1/20 0.39
GABRD O14764 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26019316 1.00 PAOX (0.56) PAOXLMNATHRBKMT2AMEN1
SCHEMBL27050934 1.00 PAOX (0.56) PAOXLMNATHRBKMT2AMEN1
SCHEMBL13300751 1.00 PAOX (0.56) PAOXLMNATHRBKMT2AMEN1
SCHEMBL800679 0.98 PAOX (0.52) PAOXLMNATHRBKMT2AMEN1
SCHEMBL800654 0.90
SCHEMBL21501562 0.88 PAOX (0.45) PAOXLMNATHRBKMT2AMEN1
SCHEMBL9973392 0.87 CES2 (0.48) LMNAKMT2AMEN1NFKB1CES2
SCHEMBL9973396 0.87 CES2 (0.48) LMNAKMT2AMEN1NFKB1CES2
SCHEMBL18751717 0.87 CES2 (0.48) LMNAKMT2AMEN1NFKB1CES2
SCHEMBL27056796 0.87 CES2 (0.48) LMNAKMT2AMEN1NFKB1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8133985-B2 Peptide nucleic acids conjugated with multi-amine linkers and nucleic acid detecting device using the same PANAGENE INC. (KR) 2012-03-13 US disclosed
US-20090312197-A1 PEPTIDE NUCLEIC ACIDS CONJUGATED WITH MULTI-AMINE LINKERS AND NUCLEIC ACID DETECTING DEVICE USING THE SAME PANAGENE INC. (KR) 2009-12-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090312197-A1 PEPTIDE NUCLEIC ACIDS CONJUGATED WITH MULTI-AMINE LINKERS AND NUCLEIC ACID DETECTING DEVICE USING THE SAME NPPA, PARN, PARG PAOX 3489/4885LMNA 559/4885THRB 1418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.