Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13300751 | 0.98 | PAOX (0.56) | PAOXCYP2D6NFKB1BLMNPSR1 | |
| SCHEMBL27050934 | 0.98 | PAOX (0.56) | PAOXCYP2D6NFKB1BLMNPSR1 | |
| SCHEMBL260557 | 0.98 | PAOX (0.56) | PAOXCYP2D6NFKB1BLMNPSR1 | |
| SCHEMBL26019316 | 0.98 | PAOX (0.56) | PAOXCYP2D6NFKB1BLMNPSR1 | |
| SCHEMBL800654 | 0.92 | — | — | |
| SCHEMBL17992598 | 0.87 | CES2 (0.44) | LMNAKMT2AMEN1LTA4HCES2 | |
| SCHEMBL21501562 | 0.86 | PAOX (0.45) | PAOXCYP2D6NFKB1BLMNPSR1 | |
| SCHEMBL9973392 | 0.84 | CES2 (0.48) | NFKB1LMNAKMT2AMEN1LTA4H | |
| SCHEMBL9973396 | 0.84 | CES2 (0.48) | NFKB1LMNAKMT2AMEN1LTA4H | |
| SCHEMBL18751717 | 0.84 | CES2 (0.48) | NFKB1LMNAKMT2AMEN1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11786547-B2 | Methods and compositions for disrupting biofilm utilizing chitosan-derivative compounds | SYNEDGEN, INC. (US) | 2023-10-17 | — | — | US | disclosed |
| US-11786547-B2 | Methods and compositions for disrupting biofilm utilizing chitosan-derivative compounds | SYNEDGEN, INC. (US) | 2023-10-17 | — | — | US | disclosed |
| US-11717532-B2 | Methods and compositions for treating wounds utilizing chitosan compounds | SYNEDGEN, INC. (US) | 2023-08-08 | — | — | US | disclosed |
| US-11717532-B2 | Methods and compositions for treating wounds utilizing chitosan compounds | SYNEDGEN, INC. (US) | 2023-08-08 | — | — | US | disclosed |
| US-20230201248-A1 | COMPOSITIONS AND METHODS OF USE THEREOF | SYNEDGEN, INC. | 2023-06-29 | — | — | US | disclosed |
| US-20230201248-A1 | COMPOSITIONS AND METHODS OF USE THEREOF | SYNEDGEN, INC. | 2023-06-29 | — | — | US | disclosed |
| US-20230181623-A1 | COMPOSITIONS AND METHODS OF USE FOR WOUND HEALING | SYNEDGEN, INC. | 2023-06-15 | — | — | US | disclosed |
| EP-2968080-B1 | ORAL FORMULATION OF POLYGLUCOSAMINE DERIVATIVES IN COMBINATION WITH A NON-FERMENTABLE SUGAR | SYNEDGEN INC (US) | 2023-05-10 | — | — | EP | disclosed |
| US-11433092-B2 | Compositions and methods of use for wound healing | SYNEDGEN, INC. (US) | 2022-09-06 | — | — | US | disclosed |
| US-20210386774-A1 | METHODS FOR TREATMENT OR PREVENTION OF DAMAGE RESULTING FROM RADIATION, TRAUMA OR SHOCK | SYNEDGEN, INC. | 2021-12-16 | — | — | US | disclosed |
| US-20120070370-A1 | SPIRO 1,3,4-THIADIAZOLINE DERIVATIVES AS KSP INHIBITORS | MERCK SHARP & DOHME CORP. | 2012-03-22 | — | — | US | disclosed |
| US-20120046291-A1 | Extended Triterpene Derivatives | MYREXIS, INC. | 2012-02-23 | — | — | US | disclosed |
| US-20110171172-A1 | COMPOUNDS FOR INHIBITING KSP KINESIN ACTIVITY | MERCK SHARP & DOHME CORP. | 2011-07-14 | — | — | US | disclosed |
| US-20110171172-A1 | COMPOUNDS FOR INHIBITING KSP KINESIN ACTIVITY | MERCK SHARP & DOHME CORP. | 2011-07-14 | — | — | US | disclosed |
| US-20110150757-A1 | COMPOUNDS FOR INHIBITING KSP KINESIN ACTIVITY | MERCK SHARP & DOHME CORP. | 2011-06-23 | — | — | US | disclosed |
| US-20110123435-A1 | COMPOUNDS FOR INHIBITING KSP KINESIN ACTIVITY | MERCK SHARP & DOHME LLC | 2011-05-26 | — | — | US | disclosed |
| WO-2011028967-A1 | METHODS AND COMPOSITIONS FOR DISRUPTING BIOFILM UTILIZING CHITOSAN-DERIVATIVE COMPOUNDS | SYNEDGEN INC. (US) | 2011-03-10 | — | — | WO | disclosed |
| US-20100137193-A1 | CHITOSAN DERIVATIVES TO TREAT ANIMALS OR OPTIMIZE ANIMAL HEALTH | SYNEDGEN INC. (US) | 2010-06-03 | — | — | US | disclosed |
| US-20100130443-A1 | CHITOSAN DERIVATIVES, COMPOSITIONS AND RELATED METHODS OF USE | SYNEDGEN INC. (US) | 2010-05-27 | — | — | US | disclosed |
| US-20100056474-A1 | Methods and Compositions for the Prevention of and Treatment of Infections Utilizing Chitosan-Derivative Compounds | UNITED STATES GOVERNMENT | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11433092-B2 | Compositions and methods of use for wound healing | PARG, ARGLU1, AREG | PAOX 1447/4885CYP2D6 4856/4885NFKB1 915/4885 |
| US-20110150757-A1 | COMPOUNDS FOR INHIBITING KSP KINESIN ACTIVITY | KIF18B, KIF5B, KIF18A | PAOX 3555/4885CYP2D6 4517/4885NFKB1 2141/4885 |
| US-20120070370-A1 | SPIRO 1,3,4-THIADIAZOLINE DERIVATIVES AS KSP INHIBITORS | KIF2C, SKP1, KIF5B | PAOX 3200/4885CYP2D6 4281/4885NFKB1 2214/4885 |
| US-20230181623-A1 | COMPOSITIONS AND METHODS OF USE FOR WOUND HEALING | PARG, ARGLU1, AREG | PAOX 1447/4885CYP2D6 4856/4885NFKB1 915/4885 |
| US-20210386774-A1 | METHODS FOR TREATMENT OR PREVENTION OF DAMAGE RESULTING FROM RADIATION, TRAUMA OR SHOCK | HMGB1, ELANE, SERPINB1 | PAOX 2674/4885CYP2D6 4038/4885NFKB1 174/4885 |
| US-20100137193-A1 | CHITOSAN DERIVATIVES TO TREAT ANIMALS OR OPTIMIZE ANIMAL HEALTH | CHIT1, CHIA, ALG1 | PAOX 2415/4885CYP2D6 4236/4885NFKB1 627/4885 |
| US-20110123435-A1 | COMPOUNDS FOR INHIBITING KSP KINESIN ACTIVITY | KIF5B, KIF2C, KIFC1 | PAOX 3234/4885CYP2D6 4566/4885NFKB1 2052/4885 |
| US-20100056474-A1 | Methods and Compositions for the Prevention of and Treatment of Infections Utilizing Chitosan-Derivative Compounds | NRDC, ARG1, CHIA | PAOX 4010/4885CYP2D6 3218/4885NFKB1 1630/4885 |
| US-20120046291-A1 | Extended Triterpene Derivatives | BET1, PGGT1B, TMPO | PAOX 1609/4885CYP2D6 417/4885NFKB1 860/4885 |
| US-20110171172-A1 | COMPOUNDS FOR INHIBITING KSP KINESIN ACTIVITY | KIF5B, KIF2C, KIFC1 | PAOX 3535/4885CYP2D6 4580/4885NFKB1 1779/4885 |
| US-11717532-B2 | Methods and compositions for treating wounds utilizing chitosan compounds | CHIA, MMP8, CHIT1 | PAOX 2479/4885CYP2D6 4572/4885NFKB1 1791/4885 |
| US-20230201248-A1 | COMPOSITIONS AND METHODS OF USE THEREOF | ENGASE, FUT5, ALG1 | PAOX 585/4885CYP2D6 3041/4885NFKB1 3142/4885 |
| US-11786547-B2 | Methods and compositions for disrupting biofilm utilizing chitosan-derivative compounds | CHIT1, ALG1, CSGALNACT1 | PAOX 3756/4885CYP2D6 4313/4885NFKB1 3153/4885 |
| US-20100130443-A1 | CHITOSAN DERIVATIVES, COMPOSITIONS AND RELATED METHODS OF USE | CHIT1, CHIA, ALG1 | PAOX 3569/4885CYP2D6 2557/4885NFKB1 2681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.