Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26019316 | 1.00 | PAOX (0.56) | PAOXLMNATHRBKMT2AMEN1 | |
| SCHEMBL260557 | 1.00 | PAOX (0.56) | PAOXLMNATHRBKMT2AMEN1 | |
| SCHEMBL27050934 | 1.00 | PAOX (0.56) | PAOXLMNATHRBKMT2AMEN1 | |
| SCHEMBL800679 | 0.98 | PAOX (0.52) | PAOXLMNATHRBKMT2AMEN1 | |
| SCHEMBL800654 | 0.90 | — | — | |
| SCHEMBL21501562 | 0.88 | PAOX (0.45) | PAOXLMNATHRBKMT2AMEN1 | |
| SCHEMBL9973392 | 0.87 | CES2 (0.48) | LMNAKMT2AMEN1NFKB1CES2 | |
| SCHEMBL9973396 | 0.87 | CES2 (0.48) | LMNAKMT2AMEN1NFKB1CES2 | |
| SCHEMBL18751717 | 0.87 | CES2 (0.48) | LMNAKMT2AMEN1NFKB1CES2 | |
| SCHEMBL27056796 | 0.87 | CES2 (0.48) | LMNAKMT2AMEN1NFKB1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11911412-B2 | Derivatized chitosan polymers and methods of treating vascular disorders | SYNEDGEN, INC. (US) | 2024-02-27 | — | — | US | disclosed |
| EP-4269407-A1 | NEAR-INFRARED FLUORESCENT PROBE SPECIFICALLY TARGETING TUMOR, SYNTHESIS METHOD THEREFOR, AND USE THEREOF | Nanjing Nuoyuan Medical Instrument Co., Ltd (CN) | 2023-11-01 | — | — | EP | disclosed |
| US-11786547-B2 | Methods and compositions for disrupting biofilm utilizing chitosan-derivative compounds | SYNEDGEN, INC. (US) | 2023-10-17 | — | — | US | disclosed |
| US-11786547-B2 | Methods and compositions for disrupting biofilm utilizing chitosan-derivative compounds | SYNEDGEN, INC. (US) | 2023-10-17 | — | — | US | disclosed |
| US-11717532-B2 | Methods and compositions for treating wounds utilizing chitosan compounds | SYNEDGEN, INC. (US) | 2023-08-08 | — | — | US | disclosed |
| US-11717532-B2 | Methods and compositions for treating wounds utilizing chitosan compounds | SYNEDGEN, INC. (US) | 2023-08-08 | — | — | US | disclosed |
| US-11433092-B2 | Compositions and methods of use for wound healing | SYNEDGEN, INC. (US) | 2022-09-06 | — | — | US | disclosed |
| US-20220160754-A1 | DERIVATIZED CHITOSAN POLYMERS AND METHODS OF TREATING VASCULAR DISORDERS | SYNEDGEN, INC. | 2022-05-26 | — | — | US | disclosed |
| US-20210386774-A1 | METHODS FOR TREATMENT OR PREVENTION OF DAMAGE RESULTING FROM RADIATION, TRAUMA OR SHOCK | SYNEDGEN, INC. | 2021-12-16 | — | — | US | disclosed |
| WO-2021221656-A1 | COMPOSITIONS AND METHODS OF USE THEREOF | SYNEDGEN, INC. (US) | 2021-11-04 | — | — | WO | disclosed |
| US-20120301408-A1 | ORAL CARE METHODS AND COMPOSITIONS UTILIZING CHITOSAN-DERIVATIVE COMPOUNDS | UNITED STATES GOVERNMENT | 2012-11-29 | — | — | US | disclosed |
| US-20120295355-A1 | NUCLEIC ACID DELIVERY USING MODIFIED CHITOSANS | BAKER SHENDA (US) | 2012-11-22 | — | — | US | disclosed |
| US-20120078296-A1 | BIOMIMETIC COMPOUNDS AND SYNTHETIC METHODS THEREFOR | KNC NER ACQUISITION SUB, INC. (US) | 2012-03-29 | — | — | US | disclosed |
| US-20120003888-A1 | BIOADHESIVE CONSTRUCTS WITH POLYMER BLENDS | KNC NER ACQUISITION SUB, INC. (US) | 2012-01-05 | — | — | US | disclosed |
| US-20100137193-A1 | CHITOSAN DERIVATIVES TO TREAT ANIMALS OR OPTIMIZE ANIMAL HEALTH | SYNEDGEN INC. (US) | 2010-06-03 | — | — | US | disclosed |
| US-20100130443-A1 | CHITOSAN DERIVATIVES, COMPOSITIONS AND RELATED METHODS OF USE | SYNEDGEN INC. (US) | 2010-05-27 | — | — | US | disclosed |
| US-20100087466-A1 | NOVEL SMALL MOLECULE DNAK INHIBITORS | CHAPERONE TECHNOLOGIES, INC. | 2010-04-08 | — | — | US | disclosed |
| US-20100087466-A1 | NOVEL SMALL MOLECULE DNAK INHIBITORS | CHAPERONE TECHNOLOGIES, INC. | 2010-04-08 | — | — | US | disclosed |
| US-20100056474-A1 | Methods and Compositions for the Prevention of and Treatment of Infections Utilizing Chitosan-Derivative Compounds | UNITED STATES GOVERNMENT | 2010-03-04 | — | — | US | disclosed |
| US-20090054319-A1 | Methods and Compositions for the Treatment of Hypertension and Gastrointestinal Disorders | MICROBIA, INC. (US) | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11433092-B2 | Compositions and methods of use for wound healing | PARG, ARGLU1, AREG | PAOX 1447/4885LMNA 2017/4885THRB 3562/4885 |
| US-20210386774-A1 | METHODS FOR TREATMENT OR PREVENTION OF DAMAGE RESULTING FROM RADIATION, TRAUMA OR SHOCK | HMGB1, ELANE, SERPINB1 | PAOX 2674/4885LMNA 843/4885THRB 1554/4885 |
| US-20100137193-A1 | CHITOSAN DERIVATIVES TO TREAT ANIMALS OR OPTIMIZE ANIMAL HEALTH | CHIT1, CHIA, ALG1 | PAOX 2415/4885LMNA 1960/4885THRB 3320/4885 |
| US-20220160754-A1 | DERIVATIZED CHITOSAN POLYMERS AND METHODS OF TREATING VASCULAR DISORDERS | CHIA, CHI3L1, CHI3L2 | PAOX 2722/4885LMNA 927/4885THRB 4427/4885 |
| US-20100056474-A1 | Methods and Compositions for the Prevention of and Treatment of Infections Utilizing Chitosan-Derivative Compounds | NRDC, ARG1, CHIA | PAOX 4010/4885LMNA 1677/4885THRB 3122/4885 |
| US-20100087466-A1 | NOVEL SMALL MOLECULE DNAK INHIBITORS | HSP90AB2P, HSPH1, HSP90AB1 | PAOX 2096/4885LMNA 4794/4885THRB 3525/4885 |
| US-20120301408-A1 | ORAL CARE METHODS AND COMPOSITIONS UTILIZING CHITOSAN-DERIVATIVE COMPOUNDS | CHIT1, ALG1, SI | PAOX 2132/4885LMNA 3102/4885THRB 3101/4885 |
| US-11717532-B2 | Methods and compositions for treating wounds utilizing chitosan compounds | CHIA, MMP8, CHIT1 | PAOX 2479/4885LMNA 1695/4885THRB 4402/4885 |
| US-11786547-B2 | Methods and compositions for disrupting biofilm utilizing chitosan-derivative compounds | CHIT1, ALG1, CSGALNACT1 | PAOX 3756/4885LMNA 1653/4885THRB 4052/4885 |
| US-20100130443-A1 | CHITOSAN DERIVATIVES, COMPOSITIONS AND RELATED METHODS OF USE | CHIT1, CHIA, ALG1 | PAOX 3569/4885LMNA 3640/4885THRB 4509/4885 |
| US-11911412-B2 | Derivatized chitosan polymers and methods of treating vascular disorders | CHIA, CHI3L1, CHI3L2 | PAOX 2722/4885LMNA 927/4885THRB 4427/4885 |
| US-20090054319-A1 | Methods and Compositions for the Treatment of Hypertension and Gastrointestinal Disorders | PTGIS, PTGIR, GRPR | PAOX 2490/4885LMNA 2833/4885THRB 2016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.