SCHEMBL2605572

SCHEMBL2605572

COCc1cc(C(c2cc(C(C)=O)c(O)c(C(C)=O)c2)(C(F)(F)F)C(F)(F)F)cc(COC)c1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCE Q02156 3/20 0.42
MYLK Q15746 2/20 0.37
MAPT P10636 2/20 0.37
ALDH1A1 P00352 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
PRKCG P05129 1/20 0.37
PRKCA P17252 1/20 0.37
APEX1 P27695 1/20 0.37
RECQL P46063 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
HTT P42858 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CYP3A4 P08684 1/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
KDM4E B2RXH2 1/20 0.31
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2463085 0.87 PRKCE (0.43) PRKCEMYLKMAPTALDH1A1MEN1
SCHEMBL2605563 0.84 PRKCE (0.45) PRKCEMYLKMAPTALDH1A1MEN1
SCHEMBL14081747 0.84 PRKCE (0.45) PRKCEMYLKMAPTALDH1A1MEN1
SCHEMBL2605568 0.83 PRKCE (0.44) PRKCEMYLKMAPTALDH1A1MEN1
SCHEMBL14081748 0.81 PRKCE (0.42) PRKCEMYLKMAPTALDH1A1MEN1
SCHEMBL19410118 0.81 PRKCE (0.41) PRKCEMYLKMAPTALDH1A1MEN1
SCHEMBL14028983 0.80 PRKCE (0.44) PRKCEMYLKMAPTALDH1A1MEN1
SCHEMBL2605571 0.80 PRKCE (0.46) PRKCEMYLKMAPTALDH1A1MEN1
SCHEMBL12937583 0.78 PRKCE (0.37) PRKCEMYLKMAPTALDH1A1MEN1
SCHEMBL2464772 0.78 ESR1 (0.36) PRKCEALDH1A1HTTCYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8158324-B2 Positive-type photosensitive resin composition TORAY INDUSTRIES, INC. (JP) 2012-04-17 US disclosed
US-20100099041-A1 POSITIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION TORAY INDUSTRIES, INC. (JP) 2010-04-22 US disclosed