Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12864217 | 0.92 | POLB (0.47) | VNN1POLBCNR2ESR1ESR2 | |
| SCHEMBL2606066 | 0.85 | PDK2 (0.41) | CNR2ATMTDP1L3MBTL1PDK2 | |
| SCHEMBL12864215 | 0.83 | ESR1 (0.46) | VNN1POLBESR1ESR2KMT2A | |
| SCHEMBL2605937 | 0.80 | CHRM5 (0.37) | VNN1POLBCNR2ESR1ESR2 | |
| SCHEMBL12864224 | 0.79 | CES2 (0.45) | POLBESR1ESR2KMT2AATM | |
| SCHEMBL2605984 | 0.79 | ALDH1A1 (0.48) | CNR2ESR1ESR2CNR1KMT2A | |
| SCHEMBL1167840 | 0.78 | TDP1 (0.52) | POLBCNR2ESR1ESR2CNR1 | |
| SCHEMBL10053610 | 0.78 | PDK2 (0.40) | POLBESR1ESR2KMT2AATM | |
| SCHEMBL13649845 | 0.78 | PDK2 (0.40) | POLBESR1ESR2KMT2AATM | |
| SCHEMBL2606070 | 0.77 | SRD5A2 (0.41) | POLBCNR2ESR1ESR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2260023-B1 | FLUORENE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2012-04-25 | — | — | EP | disclosed |