SCHEMBL26060417

SCHEMBL26060417

Cc1ccccc1-c1c2ccc(CC(C)C)cc2nc[n+]1C

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.32
ALOX5AP P20292 1/20 0.31
KDM4E B2RXH2 2/20 0.31
MAPK14 Q16539 2/20 0.31
PTGES O14684 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
LCK P06239 1/20 0.30
KDR P35968 1/20 0.30
JAK3 P52333 1/20 0.30
NR3C2 P08235 1/20 0.30
POLB P06746 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
EDNRA P25101 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26813596 0.91 CYP3A4 (0.33) DHODHALOX5APKDM4EMAPK14LCK
SCHEMBL26060531 0.84 AAK1 (0.34) MAPK14
SCHEMBL25518863 0.83 KDM4E (0.31) KDM4EPOLBSMN1; SMN2
SCHEMBL26060418 0.82 MAPK14 (0.31) MAPK14PTGESLCKKDRJAK3
SCHEMBL25716794 0.81 AAK1 (0.30)
SCHEMBL26060419 0.81 LMNA (0.39) MAPK14PTGESLCKKDRJAK3
SCHEMBL26813690 0.80 HTR1A (0.38) MAPK14PTGESLCKKDRJAK3
SCHEMBL26060446 0.80 PDE2A (0.33) MAPK14
SCHEMBL26060421 0.79 GRM2 (0.33) MAPK14
SCHEMBL25443013 0.79 HTR2A (0.33) DHODHGABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11832456-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 US disclosed
US-20230287263-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
US-11692132-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11832456-B2 Organic electroluminescent materials and devices CPNE4, CYBA, EPCAM DHODH 2570/4885ALOX5AP 1680/4885KDM4E 807/4885
US-11692132-B2 Organic electroluminescent materials and devices OSBP, OCIAD1, OCIAD2 DHODH 1164/4885ALOX5AP 2029/4885KDM4E 4627/4885
US-20230287263-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OCIAD1, OCIAD2 DHODH 1164/4885ALOX5AP 2029/4885KDM4E 4627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.