SCHEMBL26060418

SCHEMBL26060418

Cc1ccccc1-c1c2ccc(CC(C)(C)C)cc2nc[n+]1C

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 2/20 0.31
PTGES O14684 1/20 0.31
LCK P06239 1/20 0.30
KDR P35968 1/20 0.30
JAK3 P52333 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26060421 0.88 GRM2 (0.33) MAPK14
SCHEMBL26060533 0.84 AAK1 (0.32) MAPK14
SCHEMBL25518900 0.83
SCHEMBL26060417 0.82 DHODH (0.32) MAPK14PTGESLCKKDRJAK3
SCHEMBL26060446 0.82 PDE2A (0.33) MAPK14
SCHEMBL26813690 0.80 HTR1A (0.38) MAPK14PTGESLCKKDRJAK3
SCHEMBL25443558 0.79
SCHEMBL25445415 0.78 ADORA2A (0.41)
SCHEMBL25445494 0.76 PI4KA (0.39) MAPK14PTGESLCKKDRJAK3
SCHEMBL26060419 0.75 LMNA (0.39) MAPK14PTGESLCKKDRJAK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230287263-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
US-11692132-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11692132-B2 Organic electroluminescent materials and devices OSBP, OCIAD1, OCIAD2 MAPK14 4061/4885PTGES 2138/4885LCK 939/4885
US-20230287263-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OCIAD1, OCIAD2 MAPK14 4061/4885PTGES 2138/4885LCK 939/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.