SCHEMBL26060419

SCHEMBL26060419

Cc1ccccc1-c1c2ccc(C(C)C)cc2nc[n+]1C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.39
CLK4 Q9HAZ1 3/20 0.34
LCK P06239 2/20 0.34
KDR P35968 2/20 0.34
AURKA O14965 1/20 0.34
DAPK3 O43293 1/20 0.34
JAK2 O60674 1/20 0.34
MAP4K4 O95819 1/20 0.34
PAK4 O96013 1/20 0.34
ABL1 P00519 1/20 0.34
FYN P06241 1/20 0.34
CSF1R P07333 1/20 0.34
RET P07949 1/20 0.34
IGF1R P08069 1/20 0.34
FLT1 P17948 1/20 0.34
LTK P29376 1/20 0.34
FLT3 P36888 1/20 0.34
MAPK8 P45983 1/20 0.34
MAPK9 P45984 1/20 0.34
CLK2 P49760 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26813698 0.91 LMNA (0.38) LMNACLK4LCKKDRAURKA
SCHEMBL26060534 0.83 LMNA (0.36) LMNACLK4LCKKDRAURKA
SCHEMBL26813690 0.83 HTR1A (0.38) LMNACLK4LCKKDRMAPK14
SCHEMBL25518862 0.82 LMNA (0.34) LMNACLK4LCKKDRAURKA
SCHEMBL25445415 0.81 ADORA2A (0.41) LMNACLK4CYP1A2CYP3A4CYP2D6
SCHEMBL26060417 0.81 DHODH (0.32) LCKKDRMAPK14PTGESJAK3
SCHEMBL26060554 0.80 LMNA (0.33) LMNACLK4LCKKDRAURKA
SCHEMBL25445494 0.79 PI4KA (0.39) LCKKDRMAPK14PTGESJAK3
SCHEMBL25442958 0.77 LMNA (0.40) LMNAKIF11CRHR1TRPA1PTGS1
SCHEMBL26813692 0.76 CYP1A2 (0.38) LMNACLK4LCKKDRMAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11832456-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 US disclosed
US-20230287263-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
US-11692132-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11832456-B2 Organic electroluminescent materials and devices CPNE4, CYBA, EPCAM LMNA 2800/4885CLK4 1282/4885LCK 335/4885
US-11692132-B2 Organic electroluminescent materials and devices OSBP, OCIAD1, OCIAD2 LMNA 4455/4885CLK4 1827/4885LCK 939/4885
US-20230287263-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OCIAD1, OCIAD2 LMNA 4455/4885CLK4 1827/4885LCK 939/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.