SCHEMBL25518862

SCHEMBL25518862

Cc1cc(C)c(C)c(-c2c3ccc(C(C)C)cc3nc[n+]2C)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.34
AURKA O14965 1/20 0.33
DAPK3 O43293 1/20 0.33
JAK2 O60674 1/20 0.33
MAP4K4 O95819 1/20 0.33
PAK4 O96013 1/20 0.33
ABL1 P00519 1/20 0.33
LCK P06239 1/20 0.33
FYN P06241 1/20 0.33
CSF1R P07333 1/20 0.33
RET P07949 1/20 0.33
IGF1R P08069 1/20 0.33
FLT1 P17948 1/20 0.33
LTK P29376 1/20 0.33
KDR P35968 1/20 0.33
FLT3 P36888 1/20 0.33
MAPK8 P45983 1/20 0.33
MAPK9 P45984 1/20 0.33
CLK2 P49760 1/20 0.33
GSK3A P49840 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25518861 0.85 HTR1A (0.37) LMNA
SCHEMBL26060554 0.82 LMNA (0.33) LMNAAURKADAPK3JAK2MAP4K4
SCHEMBL25518935 0.82 NSD3 (0.33) ABL1CDK5
SCHEMBL26060419 0.82 LMNA (0.39) LMNAAURKADAPK3JAK2MAP4K4
SCHEMBL25518863 0.81 KDM4E (0.31)
SCHEMBL25518830 0.81 PSMB5 (0.36) LMNAACVR1
SCHEMBL26300845 0.81 LMNA (0.33) LMNATRPA1PTGS1CACNA1C
SCHEMBL26060534 0.79 LMNA (0.36) LMNAAURKADAPK3JAK2MAP4K4
SCHEMBL25442960 0.78 LMNA (0.35) LMNATRPA1PTGS1CACNA1C
SCHEMBL25518900 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230348508-A1 METAL COMPLEX, ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME, AND CONSUMER PRODUCT BEIJING BAYI SPACE LIQUID CRYSTAL TECHNOLOGY CO. LTD. (CN) 2023-11-02 US disclosed
US-20230309394-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 US disclosed
US-20230295204-A1 METAL COMPLEX AND USE THEREOF GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD (CN) 2023-09-21 US disclosed
US-20230287263-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
US-11692132-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-04 US disclosed
US-20230200227-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-06-22 US disclosed
US-20230144101-A1 LIGHT-EMITTING MATERIAL WITH A POLYCYCLIC LIGAND Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-05-11 US disclosed
US-20230136831-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-05-04 US disclosed
EP-4174078-A1 ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-05-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230295204-A1 METAL COMPLEX AND USE THEREOF IK, CYBA, LAS1L LMNA 670/4885AURKA 2224/4885DAPK3 4241/4885
US-11692132-B2 Organic electroluminescent materials and devices OSBP, OCIAD1, OCIAD2 LMNA 4455/4885AURKA 2240/4885DAPK3 1749/4885
US-20230144101-A1 LIGHT-EMITTING MATERIAL WITH A POLYCYCLIC LIGAND TRPC4, CRY1, TRPC1 LMNA 718/4885AURKA 2628/4885DAPK3 3502/4885
US-20230348508-A1 METAL COMPLEX, ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME, AND CONSUMER PRODUCT TRPM5, TRPM6, TRPM2 LMNA 2853/4885AURKA 2045/4885DAPK3 4703/4885
US-20230287263-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OCIAD1, OCIAD2 LMNA 4455/4885AURKA 2240/4885DAPK3 1749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.