Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21250118 | 0.82 | SCN8A (0.34) | CXCR4 | |
| SCHEMBL22222003 | 0.76 | ALDH1A1 (0.33) | TRPM8 | |
| SCHEMBL21250137 | 0.75 | ESR1 (0.32) | CXCR4 | |
| SCHEMBL19346224 | 0.71 | TRPM8 (0.36) | TRPM8CXCR4 | |
| SCHEMBL4547925 | 0.69 | TRPM8 (0.47) | TRPM8CXCR4 | |
| SCHEMBL22894786 | 0.69 | NR3C2 (0.31) | — | |
| SCHEMBL14519455 | 0.68 | TRPM8 (0.42) | TRPM8CXCR4 | |
| SCHEMBL23025588 | 0.68 | RXRA (0.30) | — | |
| SCHEMBL15034700 | 0.66 | TRPM8 (0.37) | TRPM8CXCR4SCN9A | |
| SCHEMBL18812906 | 0.65 | CXCR4 (0.33) | CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250129-A1 | NEUROACTIVE STEROIDS AND COMPOSITIONS THEREOF | SAGE THERAPEUTICS, INC. | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250129-A1 | NEUROACTIVE STEROIDS AND COMPOSITIONS THEREOF | MC2R, NR3C2, AVPR1B | TRPM8 2253/4885CXCR4 784/4885SCN9A 390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.