Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2603485 | 0.79 | EGFR (0.51) | GAAL3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2818516 | 0.78 | GAA (0.51) | GAAL3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3684471 | 0.74 | GAA (0.51) | GAAL3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL20482131 | 0.70 | RAB9A (0.56) | GAAL3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29785125 | 0.69 | ESR1 (0.58) | GAAL3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1192488 | 0.69 | ESR1 (0.58) | GAAL3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL13528421 | 0.68 | L3MBTL1 (0.82) | GAAL3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL903255 | 0.68 | NPC1 (0.61) | GAAL3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9105844 | 0.68 | NPC1 (0.61) | GAAL3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29442076 | 0.68 | NPC1 (0.61) | GAAL3MBTL1RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158664-B2 | Antimicrobial and radioprotective compounds | BIODIEM LTD. (AU) | 2012-04-17 | — | — | US | disclosed |
| US-20100292317-A1 | ANTIMICROBIAL AND RADIOPROTECTIVE COMPOUNDS | BIODIEM LTD. (AU) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292317-A1 | ANTIMICROBIAL AND RADIOPROTECTIVE COMPOUNDS | RAD51, BRCA1, XPA | GAA 3995/4885L3MBTL1 1444/4885RAB9A 451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.