Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.61 |
| ▸ | RAB9A | P51151 | 10/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.61 |
| ▸ | HPGD | P15428 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | CASP3 | P42574 | 2/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.58 |
| ▸ | STAT1 | P42224 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ELANE | P08246 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL903255 | 1.00 | NPC1 (0.61) | NPC1RAB9AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL29442076 | 1.00 | NPC1 (0.61) | NPC1RAB9AKDM4ESMN1; SMN2HPGD | |
| Iodide SCHEMBL8417295 | 0.98 | NPC1 (0.59) | NPC1RAB9AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL5849595 | 0.84 | L3MBTL1 (0.77) | NPC1RAB9AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL13528421 | 0.83 | L3MBTL1 (0.82) | NPC1RAB9AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL5541680 | 0.83 | KDM4E (0.63) | NPC1RAB9AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL1192488 | 0.79 | ESR1 (0.58) | NPC1RAB9AKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL353166 | 0.79 | LMNA (0.61) | NPC1RAB9AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL1133163 | 0.79 | L3MBTL1 (0.56) | NPC1RAB9AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL5543053 | 0.79 | GAA (0.56) | NPC1RAB9AKDM4ESMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527186-A4 | — | UNIV ILLINOIS (US) | 1995-01-18 | — | — | EP | disclosed |
| EP-0527186-A1 | PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS | The Board of Trustees for the University of Illinois (US) | 1993-02-17 | — | — | EP | disclosed |
| WO-1991016820-A1 | PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 1991-11-14 | — | — | WO | disclosed |