SCHEMBL903255

SCHEMBL903255

Cc1ccc2oc(C)nc2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 10/20 0.61
RAB9A P51151 10/20 0.61
KDM4E B2RXH2 7/20 0.61
SMN1; SMN2 Q16637 6/20 0.61
HPGD P15428 5/20 0.61
ALDH1A1 P00352 5/20 0.61
HSD17B10 Q99714 4/20 0.61
TP53 P04637 3/20 0.61
L3MBTL1 Q9Y468 4/20 0.59
GAA P10253 1/20 0.59
CASP3 P42574 2/20 0.58
SENP7 Q9BQF6 2/20 0.58
SENP6 Q9GZR1 2/20 0.58
POLB P06746 2/20 0.58
SENP8 Q96LD8 1/20 0.58
STAT1 P42224 1/20 0.57
MAPT P10636 4/20 0.53
ELANE P08246 1/20 0.52
NFKB1 P19838 3/20 0.51
NFKB2 Q00653 3/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29442076 1.00 NPC1 (0.61) NPC1RAB9AKDM4ESMN1; SMN2HPGD
SCHEMBL9105844 1.00 NPC1 (0.61) NPC1RAB9AKDM4ESMN1; SMN2HPGD
Iodide SCHEMBL8417295 0.98 NPC1 (0.59) NPC1RAB9AKDM4ESMN1; SMN2HPGD
SCHEMBL5849595 0.84 L3MBTL1 (0.77) NPC1RAB9AKDM4ESMN1; SMN2HPGD
SCHEMBL13528421 0.83 L3MBTL1 (0.82) NPC1RAB9AKDM4ESMN1; SMN2HPGD
SCHEMBL5541680 0.83 KDM4E (0.63) NPC1RAB9AKDM4ESMN1; SMN2HPGD
SCHEMBL1192488 0.79 ESR1 (0.58) NPC1RAB9AKDM4ESMN1; SMN2L3MBTL1
SCHEMBL353166 0.79 LMNA (0.61) NPC1RAB9AKDM4ESMN1; SMN2HPGD
SCHEMBL1133163 0.79 L3MBTL1 (0.56) NPC1RAB9AKDM4ESMN1; SMN2HPGD
SCHEMBL5543053 0.79 GAA (0.56) NPC1RAB9AKDM4ESMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 430 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108085162-B Green environment-friendly detergent 杭州新画面生物科技有限公司 2020-07-17 CN claimed
US-5939568-A Accelerated catalysis of olefinic epoxidations THE SCRIPPS RESEARCH INSTITUTE (US) 1999-08-17 US claimed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO claimed
EP-0527186-A4 UNIV ILLINOIS (US) 1995-01-18 EP claimed
EP-0527186-A1 PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS The Board of Trustees for the University of Illinois (US) 1993-02-17 EP claimed
WO-1991016820-A1 PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1991-11-14 WO claimed
US-12540073-B2 Heterogeneous hydrogen-catalyst solid fuel reaction mixture and reactor BRILLIANT LIGHT POWER, INC. (US) 2026-02-03 US disclosed
WO-2025111547-A1 2,3-DIHYDROPYROLLOPYRIDINE CARBOXAMIDE COMPOUNDS AND METHODS OF USE THEREOF RGENTA THERAPEUTICS, INC. (US) 2025-05-30 WO disclosed
WO-2024137548-A2 INHIBITORS OF JAK2 Llydaw Therapeutics, Inc. (US) 2024-06-27 WO disclosed
WO-2024105364-A1 HETEROCYCLIC INHIBITORS OF CDC-LIKE KINASES CURADEV PHARMA LTD (GB) 2024-05-23 WO disclosed
WO-2024039858-A1 ESTROGEN RECEPTOR MODULATORS AND USES THEREOF OLEMA PHARMACEUTICALS, INC. (US) 2024-02-22 WO disclosed
WO-2024028411-A1 COMBINATION THERAPY OF CDK7 INHIBITORS WITH OTHER ANTI-CANCER THERAPIES QURIENT CO., LTD. (KR) 2024-02-08 WO disclosed
EP-2775839-B1 METHODS FOR ASSESSING REPELLANT QUALITY OF ORGANIC MATERIALS AND METHODS AND COMPOSITIONS FOR REPELLING ARTHROPODS UNIV CALIFORNIA (US) 2023-12-06 EP disclosed
US-4877723-A EMULSION LAYER CONTAINING AN ALKYNYL-SUBSTITUTED HETEROCYCLIC QUATERNARY AMMONIUM SALT; DIRECT POSITIVES; REVERSAL FUJI PHOTO FILM CO., LTD. (JP) 1989-10-31 US disclosed
US-4861897-A 2-Aryloxyalkylaminobenzoxazoles and 2-aryloxyalkylaminobenzothiazoles ORTHO PHARMACEUTICAL CORPORATION (US) 1989-08-29 US disclosed
US-4828973-A DIRECT POSITIVES WITH REVERSAL PROPERTIES FUJI PHOTO FILM CO., LTD. (JP) 1989-05-09 US disclosed
EP-0017810-B1 PESTICIDAL AGENTS CONTAINING SUBSTITUTED BENZAZOLES AND APPLICATION THEREOF BAYER AG (DE) 1983-06-29 EP disclosed
US-4328219-A 2-Substituted benzazole pesticide synergists BAYER AKTIENGESELLSCHAFT (DE) 1982-05-04 US disclosed
EP-0017810-A2 Pesticidal agents containing substituted benzazoles and application thereof BAYER AG (DE) 1980-10-29 EP disclosed
US-4138552-A 4-(V-triazolyl)-styryl optical brighteners CIBA-GEIGY CORPORATION (US) 1979-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12540073-B2 Heterogeneous hydrogen-catalyst solid fuel reaction mixture and reactor SCO2, SOD1, HAO2 NPC1 3402/4885RAB9A 1741/4885KDM4E 4214/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.