Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26063139 | 0.90 | ALDH1A1 (0.34) | TSHRALDH1A1CYP2C19 | |
| SCHEMBL26063142 | 0.89 | CYP2C19 (0.35) | MMP2TSHRALDH1A1CYP2C19 | |
| SCHEMBL26063163 | 0.80 | CYP2C19 (0.38) | TSHRALDH1A1CYP2C19 | |
| SCHEMBL26063149 | 0.77 | ASAH1 (0.42) | ALDH1A1CYP2C19 | |
| SCHEMBL26063147 | 0.75 | MMP9 (0.36) | MMP2ALDH1A1CYP2C19 | |
| SCHEMBL16694192 | 0.73 | TSHR (0.42) | TSHRALDH1A1CYP2C19 | |
| SCHEMBL26063228 | 0.71 | LPO (0.32) | TSHR | |
| SCHEMBL28294395 | 0.71 | TSHR (0.38) | TSHRALDH1A1CYP2C19 | |
| SCHEMBL16694185 | 0.69 | TSHR (0.40) | TSHRALDH1A1 | |
| SCHEMBL28294389 | 0.67 | TSHR (0.36) | TSHRALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230273456-A1 | OPTICALLY ACTIVE DEVICES | JOHNSON & JOHNSON SURGICAL VISION INC (US) | 2023-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230273456-A1 | OPTICALLY ACTIVE DEVICES | PDE6C, PDE6D, PDE6A | MMP2 3263/4885TSHR 4585/4885ALDH1A1 277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.