Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26063139 | 0.99 | ALDH1A1 (0.34) | CYP2C19ALDH1A1TSHRMMP1MMP9 | |
| SCHEMBL26063145 | 0.89 | MMP2 (0.34) | CYP2C19ALDH1A1TSHRMMP2 | |
| SCHEMBL26063163 | 0.80 | CYP2C19 (0.38) | CYP2C19ALDH1A1TSHRLMNASMN1; SMN2 | |
| SCHEMBL26063149 | 0.78 | ASAH1 (0.42) | CYP2C19ALDH1A1CYP1A2GAAMEN1 | |
| SCHEMBL26550500 | 0.76 | GPR84 (0.40) | CYP2C19ALDH1A1SMN1; SMN2KMT2AGPR84 | |
| SCHEMBL26063155 | 0.76 | ALDH1A1 (0.32) | ALDH1A1TSHRLMNAGAAMEN1 | |
| SCHEMBL26063147 | 0.76 | MMP9 (0.36) | CYP2C19ALDH1A1MMP1MMP9GAA | |
| SCHEMBL16694192 | 0.74 | TSHR (0.42) | CYP2C19ALDH1A1TSHRLMNASMN1; SMN2 | |
| SCHEMBL28294395 | 0.72 | TSHR (0.38) | CYP2C19ALDH1A1TSHRCYP1A2GAA | |
| SCHEMBL26063228 | 0.72 | LPO (0.32) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230273456-A1 | OPTICALLY ACTIVE DEVICES | JOHNSON & JOHNSON SURGICAL VISION INC (US) | 2023-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230273456-A1 | OPTICALLY ACTIVE DEVICES | PDE6C, PDE6D, PDE6A | CYP2C19 1793/4885ALDH1A1 277/4885TSHR 4585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.