Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM6B | O15054 | 3/20 | 0.46 |
| ▸ | KDM4A | O75164 | 3/20 | 0.46 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.46 |
| ▸ | KDM3B | Q7LBC6 | 3/20 | 0.46 |
| ▸ | HIF1AN | Q9NWT6 | 3/20 | 0.46 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26063203 | 0.99 | KDM6B (0.47) | KDM6BKDM4AKDM4DKDM3BHIF1AN | |
| SCHEMBL26063200 | 0.78 | KDM6B (0.41) | KDM6BKDM4AKDM4DKDM3BHIF1AN | |
| SCHEMBL26039915 | 0.77 | KDM6B (0.65) | KDM6BKDM4AKDM4DKDM3BHIF1AN | |
| SCHEMBL26063205 | 0.77 | KDM6B (0.42) | KDM6BKDM4AKDM4DKDM3BHIF1AN | |
| SCHEMBL26063195 | 0.76 | GPR84 (0.64) | POLBGPR84MAPT | |
| SCHEMBL26063190 | 0.71 | ALDH1A1 (0.45) | KDM6BKDM4AKDM4DKDM3BHIF1AN | |
| SCHEMBL26063161 | 0.69 | KDM6B (0.56) | KDM6BKDM4AKDM4DKDM3BHIF1AN | |
| SCHEMBL26064122 | 0.67 | ALDH1A1 (0.41) | KDM6BKDM4AKDM4DKDM3BHIF1AN | |
| SCHEMBL23987019 | 0.64 | ALDH1A1 (0.55) | POLBALDH1A1KMT2AL3MBTL1MAPK1 | |
| SCHEMBL26064077 | 0.62 | ALDH1A1 (0.39) | KDM6BKDM4AKDM4DKDM3BHIF1AN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230273456-A1 | OPTICALLY ACTIVE DEVICES | JOHNSON & JOHNSON SURGICAL VISION INC (US) | 2023-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230273456-A1 | OPTICALLY ACTIVE DEVICES | PDE6C, PDE6D, PDE6A | KDM6B 1786/4885KDM4A 2430/4885KDM4D 1966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.