Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 7/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26064067 | 0.82 | MET (0.36) | TK1 | |
| SCHEMBL26064061 | 0.80 | GFER (0.35) | HPGDTYMP | |
| SCHEMBL26064036 | 0.79 | DUT (0.40) | — | |
| SCHEMBL26064044 | 0.78 | DUT (0.31) | — | |
| SCHEMBL24205107 | 0.74 | TSHR (0.43) | TK1TYMP | |
| SCHEMBL24205258 | 0.74 | TSHR (0.43) | TK1TYMP | |
| SCHEMBL26034683 | 0.70 | MAPK1 (0.47) | TK1MAPK1HPGDTYMP | |
| SCHEMBL456976 | 0.68 | KDM4E (0.44) | TK1MAPK1HPGDTYMP | |
| SCHEMBL17583278 | 0.68 | TYMP (0.54) | TK1MAPK1HPGDTYMP | |
| SCHEMBL24205178 | 0.67 | MAPK1 (0.45) | TK1MAPK1HPGDTYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230273456-A1 | OPTICALLY ACTIVE DEVICES | JOHNSON & JOHNSON SURGICAL VISION INC (US) | 2023-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230273456-A1 | OPTICALLY ACTIVE DEVICES | PDE6C, PDE6D, PDE6A | TK1 2551/4885MAPK1 3249/4885HPGD 65/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.