Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 10/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.31 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24205062 | 0.75 | DUT (0.43) | DUTCRBN | |
| SCHEMBL24709729 | 0.75 | DUT (0.41) | DUTALDH1A1LMNAPKMCRBN | |
| SCHEMBL24205366 | 0.73 | THRB (0.41) | DUTCRBN | |
| SCHEMBL20529215 | 0.67 | ALDH1A1 (0.44) | DUTALDH1A1LMNAPKMCRBN | |
| SCHEMBL8656960 | 0.66 | PKM (0.45) | DUTALDH1A1LMNAPKMCRBN | |
| SCHEMBL7752441 | 0.66 | PKM (0.38) | DUTALDH1A1LMNAPKMCRBN | |
| SCHEMBL1673256 | 0.66 | KMT2A (0.42) | DUTALDH1A1LMNAPKMKDM4E | |
| SCHEMBL24205321 | 0.65 | DUT (0.55) | DUTCRBN | |
| SCHEMBL6425133 | 0.64 | L3MBTL1 (0.43) | DUTALDH1A1PKMCRBNKDM4E | |
| SCHEMBL24205328 | 0.63 | DUT (0.50) | DUTCRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230273456-A1 | OPTICALLY ACTIVE DEVICES | JOHNSON & JOHNSON SURGICAL VISION INC (US) | 2023-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230273456-A1 | OPTICALLY ACTIVE DEVICES | PDE6C, PDE6D, PDE6A | DUT 1190/4885ALDH1A1 277/4885LMNA 1560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.