Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | BCR | P11274 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | BRD2 | P25440 | 2/20 | 0.38 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26064891 | 0.86 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2HSD11B1KDM4EKMT2A | |
| SCHEMBL25370107 | 0.85 | SMN1; SMN2 (0.35) | ALDH1A1SMN1; SMN2HSD11B1KDM4EABL1 | |
| SCHEMBL26065298 | 0.84 | NAMPT (0.39) | ALDH1A1SMN1; SMN2HSD11B1KDM4EMEN1 | |
| SCHEMBL26065408 | 0.83 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL26064898 | 0.83 | MEN1 (0.43) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL26065947 | 0.81 | L3MBTL1 (0.50) | ALDH1A1SMN1; SMN2HSD11B1KDM4EMEN1 | |
| SCHEMBL26065410 | 0.80 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2HSD11B1KDM4EMEN1 | |
| SCHEMBL26065925 | 0.80 | HSD11B1 (0.38) | ALDH1A1SMN1; SMN2HSD11B1KDM4EMEN1 | |
| SCHEMBL26064849 | 0.77 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2ABL1BCRMEN1 | |
| SCHEMBL26065503 | 0.76 | DDR1 (0.39) | ALDH1A1SMN1; SMN2HSD11B1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164063-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-31 | — | — | WO | disclosed |