SCHEMBL26065503

SCHEMBL26065503

Cc1ccc(S(=O)(=O)N2CCN(C3CCOCC3)CC2)c(C(F)(F)F)n1

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DDR1 Q08345 6/20 0.39
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
CNR2 P34972 5/20 0.38
CNR1 P21554 4/20 0.38
ALDH1A1 P00352 1/20 0.38
HSD11B1 P28845 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
MAPK1 P28482 1/20 0.37
NAMPT P43490 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26065512 0.89 DDR1 (0.40) DDR1MEN1KMT2AALDH1A1HSD11B1
SCHEMBL26065535 0.88 MEN1 (0.42) DDR1MEN1KMT2AALDH1A1HSD11B1
SCHEMBL25370755 0.86 MEN1 (0.33) DDR1MEN1KMT2ACNR2CNR1
SCHEMBL26065530 0.86 HSD11B1 (0.39) DDR1MEN1KMT2ACNR2ALDH1A1
SCHEMBL26065515 0.85 EBP (0.43) CNR2CNR1ALDH1A1
SCHEMBL26064898 0.82 MEN1 (0.43) MEN1KMT2AALDH1A1SMN1; SMN2MAPK1
SCHEMBL26065922 0.81 L3MBTL1 (0.46) MEN1KMT2AALDH1A1HSD11B1NAMPT
SCHEMBL26065408 0.80 ALDH1A1 (0.42) MEN1KMT2AALDH1A1SMN1; SMN2MAPK1
SCHEMBL26066128 0.80 MEN1 (0.41) DDR1MEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL26066089 0.78 ALDH1A1 (0.44) DDR1MEN1KMT2AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023164063-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2023-08-31 WO disclosed