Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | USP5 | P45974 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25372846 | 0.86 | MEN1 (0.31) | SMN1; SMN2HSD11B1KMT2AMEN1HPGD | |
| SCHEMBL26065298 | 0.85 | NAMPT (0.39) | NAMPTSMN1; SMN2HSD11B1KMT2AMEN1 | |
| SCHEMBL26065648 | 0.85 | SMN1; SMN2 (0.40) | SMN1; SMN2HSD11B1KMT2AMEN1GAA | |
| SCHEMBL26066093 | 0.83 | MEN1 (0.41) | NAMPTSMN1; SMN2HSD11B1KMT2AMEN1 | |
| SCHEMBL26066130 | 0.83 | NAMPT (0.40) | NAMPTSMN1; SMN2HSD11B1KMT2AMEN1 | |
| SCHEMBL26065642 | 0.80 | CYP3A4 (0.40) | SMN1; SMN2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL25374315 | 0.75 | TLR9 (0.31) | ALOX5APFEN1 | |
| SCHEMBL26065530 | 0.75 | HSD11B1 (0.39) | NAMPTSMN1; SMN2HSD11B1KMT2AMEN1 | |
| SCHEMBL26065641 | 0.74 | TGM2 (0.46) | — | |
| SCHEMBL26065410 | 0.73 | ALDH1A1 (0.37) | NAMPTSMN1; SMN2HSD11B1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164063-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-31 | — | — | WO | disclosed |