Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 11/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 11/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 11/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 11/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 11/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 11/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26065671 | 0.82 | PSEN1 (0.39) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL26065720 | 0.79 | ALDH1A1 (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL26065669 | 0.78 | TGM2 (0.48) | — | |
| Trifluoroacetic Acid SCHEMBL25371870 | 0.77 | PSEN1 (0.35) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL26065675 | 0.77 | PSEN1 (0.44) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| Trifluoroacetic Acid SCHEMBL30567069 | 0.77 | PSEN1 (0.35) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL26065680 | 0.77 | GCK (0.37) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL25370044 | 0.76 | CYP17A1 (0.36) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL26066081 | 0.74 | MAPT (0.43) | USP2ALDH1A1CYP3A4TSHRNFKB1 | |
| SCHEMBL26065665 | 0.73 | PSEN1 (0.40) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164063-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-31 | — | — | WO | disclosed |