Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976943 | 0.84 | KMT2A (0.48) | LMNAESR1TSHRRAB9AHSD17B10 | |
| SCHEMBL21870350 | 0.83 | RAB9A (0.64) | LMNATSHRRAB9AHSD17B10ALDH1A1 | |
| SCHEMBL30599567 | 0.83 | MAPT (0.71) | LMNARAB9AALDH1A1KDM4EMAPT | |
| SCHEMBL21870353 | 0.82 | HTT (0.56) | LMNARAB9AHSD17B10ALDH1A1KDM4E | |
| SCHEMBL12225784 | 0.79 | MAPT (0.66) | RAB9AALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL30739657 | 0.79 | MAPT (0.66) | RAB9AALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL16999576 | 0.79 | PSMB5 (0.54) | KMT2AMEN1 | |
| SCHEMBL16993932 | 0.79 | PSMB5 (0.54) | KMT2AMEN1 | |
| SCHEMBL21870338 | 0.78 | ALDH1A1 (0.64) | LMNARAB9AALDH1A1KDM4EMAPT | |
| SCHEMBL2755845 | 0.77 | MAPT (0.54) | LMNAESR1TSHRALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3628374-B1 | BCL-3 INHIBITORS | UNIV COLLEGE CARDIFF CONSULTANTS LTD (GB) | 2023-08-30 | — | — | EP | disclosed |