Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976919 | 0.91 | LMNA (0.47) | KMT2AMEN1LMNAESR1HTT | |
| SCHEMBL19976969 | 0.88 | ALDH1A1 (0.49) | KMT2AMEN1LMNAESR1HTT | |
| SCHEMBL19977031 | 0.88 | KCNMA1 (0.54) | KMT2AMEN1LMNAHTTALDH1A1 | |
| SCHEMBL19976906 | 0.87 | PGR (0.52) | KMT2AMEN1LMNAHTTALDH1A1 | |
| SCHEMBL19976950 | 0.85 | ALDH1A1 (0.51) | KMT2AMEN1LMNAESR1HTT | |
| SCHEMBL19977009 | 0.85 | KMT2A (0.53) | KMT2AMEN1LMNAHTTALDH1A1 | |
| SCHEMBL26066071 | 0.84 | LMNA (0.61) | KMT2AMEN1LMNAESR1ABL1 | |
| SCHEMBL16993932 | 0.82 | PSMB5 (0.54) | KMT2AMEN1POLB | |
| SCHEMBL16999576 | 0.82 | PSMB5 (0.54) | KMT2AMEN1POLB | |
| SCHEMBL19976976 | 0.82 | KMT2A (0.56) | KMT2AMEN1LMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |