Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCK | P27707 | 3/20 | 0.33 |
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.33 |
| ▸ | CDC25B | P30305 | 3/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 3/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18005057 | 0.89 | HTT (0.37) | DCKCTSKHTTPTPN1CDC25B | |
| SCHEMBL16399195 | 0.84 | HTT (0.46) | ALDH1A1HTTPTPN1CDC25BDUSP3 | |
| SCHEMBL18005000 | 0.81 | CTSS (0.42) | CTSKALDH1A1GAAPTPN1CDC25B | |
| SCHEMBL18005066 | 0.80 | PTGDR2 (0.31) | DCKPTGDR2 | |
| SCHEMBL18005050 | 0.80 | TGFBR1 (0.33) | ALDH1A1TGFBR1KDM4EMEN1KMT2A | |
| SCHEMBL16398345 | 0.80 | CTSK (0.47) | CTSKALDH1A1SMN1; SMN2CTSSMEN1 | |
| SCHEMBL18005054 | 0.79 | CTSS (0.42) | CTSKCTSS | |
| SCHEMBL18005044 | 0.78 | CTSS (0.49) | DCKCTSKS1PR1CTSSPTGDR2 | |
| SCHEMBL18005049 | 0.77 | DCK (0.40) | DCKKDM4EPTGDR2TP53 | |
| SCHEMBL18005048 | 0.76 | GLA (0.39) | ALDH1A1GAASMN1; SMN2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |