Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5601853 | 0.81 | MAPT (0.44) | LMNAMAPTHPGDSMN1; SMN2TDP1 | |
| SCHEMBL24656023 | 0.78 | HTR1A (0.40) | MAPK14KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL20915560 | 0.78 | ALDH1A1 (0.39) | MAPTKDM4EHPGDBLMTP53 | |
| SCHEMBL11591094 | 0.77 | MAPK14 (0.42) | LMNAMAPTPDPK1MAPK14MAPK13 | |
| SCHEMBL25681144 | 0.75 | PIM1 (0.38) | — | |
| SCHEMBL26070578 | 0.75 | CYP2A6 (0.40) | MAPTKDM4ECYP2C19TP53SMN1; SMN2 | |
| SCHEMBL13162473 | 0.71 | LRRK2 (0.46) | LMNAMAPTMKNK1 | |
| SCHEMBL20915705 | 0.71 | XDH (0.49) | LMNAMAPTKDM4ESMN1; SMN2TDP1 | |
| SCHEMBL18006010 | 0.71 | CCNC (0.40) | LMNAMAPTCCNCCDK8MAPK14 | |
| SCHEMBL23294286 | 0.70 | MAP2K4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |