Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18006436 | 0.86 | ALOX15 (0.40) | SLC22A12BRD4BRD2CREBBPGABRA5 | |
| SCHEMBL4639164 | 0.81 | MAOB (0.50) | BRD4BRD2CREBBPGABRA5LMNA | |
| SCHEMBL26071067 | 0.80 | PTGER4 (0.40) | SLC22A12MAPTSMN1; SMN2HPGDPOLB | |
| SCHEMBL26071016 | 0.79 | SLC22A12 (0.38) | SLC22A12BRD4BRD2CREBBPMAPT | |
| SCHEMBL26071083 | 0.74 | SLC22A12 (0.38) | SLC22A12MAPTSMN1; SMN2HPGDPOLB | |
| SCHEMBL4639160 | 0.74 | ALDH1A1 (0.53) | LMNAMAPTSMN1; SMN2HPGDPOLB | |
| SCHEMBL18006394 | 0.74 | ALDH1A1 (0.50) | BRD4BRD2CREBBPGABRA5LMNA | |
| SCHEMBL26071018 | 0.74 | NOTUM (0.38) | SLC22A12MAPTSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL26071092 | 0.73 | IGF1R (0.39) | SLC22A12MAPTALDH1A1IGF1RMEN1 | |
| SCHEMBL18006212 | 0.73 | GABRA5 (0.36) | BRD4GABRA5SMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |