SCHEMBL26071633

SCHEMBL26071633

CC(C)C(NC(=O)OCc1ccccc1)C(=O)NC(CC(=O)O)C(=O)CF

nearest known ligand 0.66

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 18/20 0.60
CASP7 P55210 2/20 0.59
CASP9 P55211 2/20 0.59
CASP6 P55212 2/20 0.59
CASP8 Q14790 2/20 0.59
CASP1 P29466 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29384302 1.00 CASP3 (0.60) CASP3CASP7CASP9CASP6CASP8
SCHEMBL4466395 1.00 CASP3 (0.60) CASP3CASP7CASP9CASP6CASP8
SCHEMBL24213871 0.96 CASP3 (0.56) CASP3CASP7CASP9CASP6CASP8
SCHEMBL17494194 0.96 CASP3 (0.56) CASP3CASP7CASP9CASP6CASP8
SCHEMBL14646635 0.96 CASP3 (0.56) CASP3CASP7CASP9CASP6CASP8
SCHEMBL29043505 0.91 CASP3 (0.57) CASP3CASP7CASP9CASP6CASP8
SCHEMBL30376490 0.91 CASP3 (0.57) CASP3CASP7CASP9CASP6CASP8
SCHEMBL8353502 0.90 CASP3 (0.55) CASP3CASP7CASP9CASP6CASP8
SCHEMBL23268995 0.90 CASP3 (0.60) CASP3CASP7CASP9CASP6CASP8
SCHEMBL23269036 0.90 CASP3 (0.60) CASP3CASP7CASP9CASP6CASP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250313593-A1 DIPEPTIDE DERIVATIVE COMPOSITION, PREPARATION METHOD THEREFOR, AND USE THEREOF BEIJING CONTINENT PHARMACEUTICALS CO., LTD (CN) 2025-10-09 US disclosed
EP-4520344-A1 DIPEPTIDE DERIVATIVE COMPOSITION, PREPARATION METHOD THEREFOR, AND USE THEREOF Beijing Continent Pharmaceuticals Co., Ltd. (CN) 2025-03-12 EP disclosed
CN-117045634-A Dipeptide derivative composition and preparation method and application thereof 北京康蒂尼药业股份有限公司 2023-11-14 CN disclosed
US-20230310412-A1 USE OF CASPASE INHIBITOR FOR ALLEVIATING OR TREATING OSTEOARTHRITIS LG CHEM, LTD. (KR) 2023-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230310412-A1 USE OF CASPASE INHIBITOR FOR ALLEVIATING OR TREATING OSTEOARTHRITIS CASP1, CASP2, CASP5 CASP3 6/4885CASP7 10/4885CASP9 12/4885
US-20250313593-A1 DIPEPTIDE DERIVATIVE COMPOSITION, PREPARATION METHOD THEREFOR, AND USE THEREOF VIP, NGLY1, PELP1 CASP3 3008/4885CASP7 1146/4885CASP9 2632/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.