SCHEMBL29384302

SCHEMBL29384302

CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CC(=O)O)C(=O)CF

nearest known ligand 0.66

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 18/20 0.60
CASP7 P55210 2/20 0.59
CASP9 P55211 2/20 0.59
CASP6 P55212 2/20 0.59
CASP8 Q14790 2/20 0.59
CASP1 P29466 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26071633 1.00 CASP3 (0.60) CASP3CASP7CASP9CASP6CASP8
SCHEMBL4466395 1.00 CASP3 (0.60) CASP3CASP7CASP9CASP6CASP8
SCHEMBL24213871 0.96 CASP3 (0.56) CASP3CASP7CASP9CASP6CASP8
SCHEMBL17494194 0.96 CASP3 (0.56) CASP3CASP7CASP9CASP6CASP8
SCHEMBL14646635 0.96 CASP3 (0.56) CASP3CASP7CASP9CASP6CASP8
SCHEMBL29043505 0.91 CASP3 (0.57) CASP3CASP7CASP9CASP6CASP8
SCHEMBL30376490 0.91 CASP3 (0.57) CASP3CASP7CASP9CASP6CASP8
SCHEMBL8353502 0.90 CASP3 (0.55) CASP3CASP7CASP9CASP6CASP8
SCHEMBL23268995 0.90 CASP3 (0.60) CASP3CASP7CASP9CASP6CASP8
SCHEMBL23269036 0.90 CASP3 (0.60) CASP3CASP7CASP9CASP6CASP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230310412-A1 USE OF CASPASE INHIBITOR FOR ALLEVIATING OR TREATING OSTEOARTHRITIS LG CHEM, LTD. (KR) 2023-10-05 US claimed
CN-116113413-A Use of caspase inhibitors for the alleviation or treatment of osteoarthritis 株式会社LG化学 2023-05-12 CN claimed
EP-4173622-A1 USE OF CASPASE INHIBITOR FOR ALLEVIATING OR TREATING OSTEOARTHRITIS Lg Chem, Ltd. (KR) 2023-05-03 EP claimed
WO-2022123062-A1 BLOCKING CASPASE AND/OR FASL FOR PREVENTING FATAL OUTCOME IN COVID-19 PATIENTS INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2022-06-16 WO claimed
WO-2022030987-A1 USE OF CASPASE INHIBITOR FOR ALLEVIATING OR TREATING OSTEOARTHRITIS 주식회사 엘지화학 2022-02-10 WO claimed
US-20260117095-A1 FOAM SHEET AND ADHESIVE TAPE SEKISUI CHEMICAL CO., LTD. (JP) 2026-04-30 US disclosed
EP-4499350-B1 GRIPPER UNIT, GRIPPER SYSTEM, AND METHOD OF GRIPPING AN OBJECT SONY GROUP CORP (JP) 2026-04-29 EP disclosed
US-20260070024-A1 Asymmetric Hollow Fiber Membrane SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-03-12 US disclosed
EP-4651244-A1 FILM AND REINFORCEMENT MEMBER FOR ELECTROLYTE MEMBRANES OF POLYMER ELECTROLYTE FUEL CELLS USING SAME Toyobo Co., Ltd. (JP) 2025-11-19 EP disclosed
WO-2025109964-A1 CURABLE COMPOSITION AND CURED PRODUCT 株式会社カネカ 2025-05-30 WO disclosed
CN-119856253-A Base film for semiconductor manufacturing tape 日本他喜龙希爱株式会社 2025-04-18 CN disclosed
CN-119816924-A Base film for semiconductor manufacturing tape 日本他喜龙希爱株式会社 2025-04-11 CN disclosed
EP-4045480-A1 PHARMACEUTICAL FORMULATIONS First Wave Bio, Inc. (US) 2022-08-24 EP disclosed
WO-2022123062-A1 BLOCKING CASPASE AND/OR FASL FOR PREVENTING FATAL OUTCOME IN COVID-19 PATIENTS INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2022-06-16 WO disclosed
CN-114456748-A Adhesive composition and self-adhesive protective film 张家港康得新光电材料有限公司 2022-05-10 CN disclosed
WO-2022091960-A1 LAYERED FILM AND COPPER-CLAD LAYERED SHEET 株式会社カネカ 2022-05-05 WO disclosed
US-20220105057-A1 METHODS OF TREATMENT FIRST WAVE BIO, INC. 2022-04-07 US disclosed
WO-2022054887-A1 MULTILAYER STRUCTURE AND PACKAGING CONTAINER COMPRISING SAME 株式会社クラレ 2022-03-17 WO disclosed
US-20220079897-A1 METHODS OF TREATMENT FIRST WAVE BIO, INC. 2022-03-17 US disclosed
WO-2022030987-A1 USE OF CASPASE INHIBITOR FOR ALLEVIATING OR TREATING OSTEOARTHRITIS 주식회사 엘지화학 2022-02-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230310412-A1 USE OF CASPASE INHIBITOR FOR ALLEVIATING OR TREATING OSTEOARTHRITIS CASP1, CASP2, CASP5 CASP3 6/4885CASP7 10/4885CASP9 12/4885
US-20260070024-A1 Asymmetric Hollow Fiber Membrane CUTA, CD68, DSG1 CASP3 2055/4885CASP7 809/4885CASP9 2620/4885
US-20260117095-A1 FOAM SHEET AND ADHESIVE TAPE CFL1, TIAL1, PFN1 CASP3 2551/4885CASP7 1828/4885CASP9 2457/4885
US-20220079897-A1 METHODS OF TREATMENT ACE2, ACE, SI CASP3 1001/4885CASP7 1102/4885CASP9 652/4885
US-20220105057-A1 METHODS OF TREATMENT ACE2, ACE, SI CASP3 773/4885CASP7 844/4885CASP9 399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.