Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 8/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.57 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.57 |
| ▸ | HTR1B | P28222 | 6/20 | 0.51 |
| ▸ | HTR1D | P28221 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26078369 | 0.80 | TAAR1 (0.62) | TAAR1CYP2D6ADRA2AADRA2BADRA2C | |
| SCHEMBL26078373 | 0.79 | TAAR1 (0.57) | TAAR1CYP2D6ADRA2AADRA2BADRA2C | |
| SCHEMBL26078372 | 0.76 | TAAR1 (0.57) | TAAR1CYP2D6ADRA2AADRA2BADRA2C | |
| SCHEMBL26078511 | 0.76 | TAAR1 (0.65) | TAAR1CYP2D6ADRA2AADRA2BADRA2C | |
| SCHEMBL10931658 | 0.74 | TAAR1 (0.69) | TAAR1CYP2D6ADRA2AADRA2BADRA2C | |
| SCHEMBL26078566 | 0.73 | TAAR1 (0.68) | TAAR1CYP2D6ADRA2AADRA2BADRA2C | |
| Naphazoline SCHEMBL34532 | 0.73 | TAAR1 (1.00) | TAAR1CYP2D6ADRA2AADRA2BADRA2C | |
| Naphazoline SCHEMBL29369882 | 0.73 | TAAR1 (1.00) | TAAR1CYP2D6ADRA2AADRA2BADRA2C | |
| SCHEMBL953620 | 0.72 | TAAR1 (0.68) | TAAR1CYP2D6ADRA2AADRA2BADRA2C | |
| SCHEMBL26078347 | 0.72 | ADRA1A (0.55) | TAAR1CYP2D6ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230312524-A1 | ALPHA1A-ADRENERGIC RECEPTOR AGONISTS AND METHODS OF USE | CURASEN THERAPEUTICS, INC. | 2023-10-05 | — | — | US | disclosed |
| US-20230312524-A1 | ALPHA1A-ADRENERGIC RECEPTOR AGONISTS AND METHODS OF USE | CURASEN THERAPEUTICS, INC. | 2023-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230312524-A1 | ALPHA1A-ADRENERGIC RECEPTOR AGONISTS AND METHODS OF USE | ADRA1A, ADRB1, ADRA1D | TAAR1 26/4885CYP2D6 336/4885ADRA2A 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.