Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 10/20 | 0.50 |
| ▸ | HTR1B | P28222 | 8/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PTGIR | P43119 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26078570 | 0.75 | HTR1D (0.59) | HTR1DHTR1BTAAR1CYP2D6ADRA2A | |
| SCHEMBL26078572 | 0.75 | HTR1D (0.55) | HTR1DHTR1BTAAR1CYP2D6NFKB1 | |
| SCHEMBL26078581 | 0.70 | TAAR1 (0.46) | HTR1DHTR1BTAAR1CYP2D6NFKB1 | |
| SCHEMBL26078386 | 0.70 | TAAR1 (0.46) | HTR1DHTR1BTAAR1CYP2D6NFKB1 | |
| SCHEMBL16958447 | 0.70 | CETP (0.37) | LMNAMAPK1POLBMAPT | |
| SCHEMBL26078619 | 0.69 | HTR1B (0.48) | HTR1DHTR1BTAAR1CYP2D6NFKB1 | |
| SCHEMBL16960748 | 0.69 | CYP4F2 (0.38) | LMNATSHRTP53POLB | |
| SCHEMBL5204185 | 0.68 | HTR1D (0.49) | HTR1DHTR1BTAAR1CYP2D6NFKB1 | |
| SCHEMBL16955237 | 0.67 | FFAR4 (0.33) | LMNAPOLB | |
| SCHEMBL16951517 | 0.67 | BACE1 (0.36) | LMNAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230312524-A1 | ALPHA1A-ADRENERGIC RECEPTOR AGONISTS AND METHODS OF USE | CURASEN THERAPEUTICS, INC. | 2023-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230312524-A1 | ALPHA1A-ADRENERGIC RECEPTOR AGONISTS AND METHODS OF USE | ADRA1A, ADRB1, ADRA1D | HTR1D 47/4885HTR1B 105/4885TAAR1 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.