Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | THRB | P10828 | 1/20 | 0.69 |
| ▸ | MTOR | P42345 | 1/20 | 0.69 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.69 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.69 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.69 |
| ▸ | NT5E | P21589 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.46 |
| ▸ | ALB | P02768 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.46 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL399324 | 0.84 | LMNA (0.67) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL10015791 | 0.84 | LMNA (0.67) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL399323 | 0.84 | LMNA (0.67) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL18693664 | 0.84 | LMNA (0.67) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL4879682 | 0.84 | LMNA (0.67) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL27380464 | 0.83 | LMNA (0.66) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL26080 | 0.83 | LMNA (0.66) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL26986754 | 0.83 | LMNA (0.66) | LMNATHRBMTORMDM2NCOA1 | |
| Cytarabine SCHEMBL23066241 | 0.82 | LMNA (1.00) | LMNATHRBMTORMDM2NCOA1 | |
| Cytarabine SCHEMBL17993618 | 0.82 | LMNA (1.00) | LMNATHRBMTORMDM2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010104588-A2 | COMPOSITIONS AND METHODS FOR CHARACTERIZING AND TREATING NEOPLASIA | THE JOHNS HOPKINS UNIVERSITY (US) | 2010-09-16 | — | — | WO | disclosed |
| EP-1419257-A1 | METHYLATION RESISTANT VECTORS | Geneinvent Bbl AB (SE) | 2004-05-19 | — | — | EP | disclosed |
| US-20030045497-A1 | Methylation resistant vectors | GENEINVENT BBL AB | 2003-03-06 | — | — | US | disclosed |
| WO-2003012112-A1 | METHYLATION RESISTANT VECTORS | GENEINVENT BBL AB (SE) | 2003-02-13 | — | — | WO | disclosed |
| US-5856094-A | NOVEL CELL CYCLE REGULATORY POLYNUCLEOTIDES | THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 1999-01-05 | — | — | US | disclosed |