Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ICMT | O60725 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26942233 | 0.84 | PTGS2 (0.58) | CYP1A2ALDH1A1HSD17B10POLBPKM | |
| SCHEMBL4436794 | 0.79 | HSD17B10 (0.54) | CYP1A2ALDH1A1HSD17B10POLBPKM | |
| SCHEMBL11497783 | 0.79 | PTGS2 (0.61) | ALDH1A1PTGS2LMNACYP3A4TSHR | |
| SCHEMBL23531271 | 0.78 | PTGS2 (0.40) | ALDH1A1POLBPTGS2LMNATSHR | |
| SCHEMBL13784467 | 0.77 | POLB (0.46) | CYP1A2ALDH1A1HSD17B10POLBPKM | |
| SCHEMBL14273049 | 0.76 | CYP1A2 (0.73) | CYP1A2ALDH1A1HSD17B10POLBKMT2A | |
| SCHEMBL17052733 | 0.76 | PTGS2 (0.50) | ALDH1A1HSD17B10POLBPKMALOX15 | |
| SCHEMBL11724672 | 0.75 | KMT2A (0.65) | CYP1A2ALDH1A1POLBPKMKMT2A | |
| SCHEMBL226117 | 0.74 | POLB (0.64) | CYP1A2ALDH1A1POLBALOX15KMT2A | |
| SCHEMBL28451989 | 0.74 | CA12 (0.50) | ALDH1A1POLBKMT2ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11779565-B2 | Small organic molecules for use in the treatment of neuroinflammatory disorders | The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center (IL) | 2023-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11779565-B2 | Small organic molecules for use in the treatment of neuroinflammatory disorders | BMP1, BMP2, BMP4 | CYP1A2 4671/4885ALDH1A1 3914/4885HSD17B10 4080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.