SCHEMBL26083337

SCHEMBL26083337

Bc1nc(-c2ccccc2)ccc1C(C)(C)C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.45
KMT2A Q03164 6/20 0.45
RAB9A P51151 3/20 0.45
MAPT P10636 2/20 0.40
TSHR P16473 1/20 0.40
ATM Q13315 1/20 0.40
ALDH1A1 P00352 3/20 0.40
ASIC3 Q9UHC3 1/20 0.38
ADORA2A P29274 3/20 0.37
ADORA1 P30542 3/20 0.37
ADORA3 P0DMS8 1/20 0.37
GRM2 Q14416 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
AURKA O14965 1/20 0.36
HSP90AA1 P07900 1/20 0.36
PRKACA P17612 1/20 0.36
HSD17B10 Q99714 1/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
NPC1 O15118 2/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26354549 0.82 MEN1 (0.39) MEN1KMT2ARAB9AMAPTTSHR
SCHEMBL23746888 0.81 MEN1 (0.46) MEN1KMT2ARAB9AMAPTTSHR
SCHEMBL25456463 0.77 MEN1 (0.41) MEN1KMT2ARAB9AMAPTTSHR
SCHEMBL12403549 0.73 RAB9A (0.45) MEN1KMT2ARAB9AALDH1A1ASIC3
SCHEMBL25029048 0.72 CLK1 (0.35)
SCHEMBL18053301 0.69 MEN1 (0.45) MEN1KMT2ARAB9AMAPTTSHR
SCHEMBL12029666 0.68 AKT1 (0.44) MEN1KMT2AMAPTTSHRALDH1A1
SCHEMBL7814795 0.68 MEN1 (0.60) MEN1KMT2ARAB9AMAPTTSHR
SCHEMBL26354510 0.68 ALDH1A1 (0.46) MEN1KMT2ARAB9AMAPTTSHR
SCHEMBL2696016 0.68 MAP2K3 (0.49) MEN1KMT2ARAB9AMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230312627-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230312627-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF LEF1, CTCF, DNMT1 MEN1 2740/4885KMT2A 429/4885RAB9A 528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.