SCHEMBL26354549

SCHEMBL26354549

Bc1nc(-c2ccccc2)ccc1C(C)(CC)CC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.39
KMT2A Q03164 7/20 0.39
RAB9A P51151 4/20 0.39
GRM2 Q14416 1/20 0.36
ALDH1A1 P00352 6/20 0.36
NLRP3 Q96P20 1/20 0.35
ASIC3 Q9UHC3 1/20 0.34
MAPT P10636 4/20 0.34
KDM4E B2RXH2 3/20 0.34
POLB P06746 1/20 0.34
PKM P14618 1/20 0.34
DUSP10 Q9Y6W6 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
HPGD P15428 2/20 0.33
HSD17B10 Q99714 2/20 0.33
NPC1 O15118 2/20 0.33
HTT P42858 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TP53 P04637 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26083337 0.82 MEN1 (0.45) MEN1KMT2ARAB9AGRM2ALDH1A1
SCHEMBL26354510 0.73 ALDH1A1 (0.46) MEN1KMT2ARAB9AGRM2ALDH1A1
SCHEMBL25456463 0.71 MEN1 (0.41) MEN1KMT2ARAB9AGRM2ALDH1A1
SCHEMBL22674922 0.70 LDHA (0.41) MEN1KMT2ARAB9AALDH1A1ASIC3
SCHEMBL24040176 0.69 AKT1 (0.37) MEN1KMT2ARAB9AALDH1A1MAPT
SCHEMBL23746888 0.68 MEN1 (0.46) MEN1KMT2ARAB9AGRM2ALDH1A1
SCHEMBL22079742 0.68 LDHA (0.42)
SCHEMBL26290575 0.68 LDHA (0.49) MEN1KMT2ARAB9AALDH1A1MAPT
SCHEMBL25884943 0.68 LDHA (0.45) MEN1KMT2ARAB9AALDH1A1MAPT
SCHEMBL8679597 0.67 DPP4 (0.42) ALDH1A1SMN1; SMN2HPGDHSD17B10MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309375-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309375-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF LEF1, L1CAM, PIEZO1 MEN1 620/4885KMT2A 2108/4885RAB9A 2516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.