Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | CDC25A | P30304 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HK2 | P52789 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26083368 | 0.65 | ALOX5 (0.32) | — | |
| SCHEMBL6930495 | 0.63 | CHRM2 (0.44) | MCL1MAOAMAOBIDO1 | |
| SCHEMBL16772616 | 0.59 | MEN1 (0.64) | PTPN1HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL10338501 | 0.58 | BACE1 (0.52) | PTPN1HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL28689603 | 0.58 | HDAC4 (0.48) | PTPN1HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL7634679 | 0.57 | BACE1 (0.62) | PTPN1HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL29884376 | 0.57 | PDE4B (0.62) | PTPN1MCL1HDAC4HDAC2HDAC8 | |
| SCHEMBL14870490 | 0.57 | POLB (0.43) | MCL1 | |
| SCHEMBL17866726 | 0.57 | PDE4B (0.62) | PTPN1MCL1HDAC4HDAC2HDAC8 | |
| SCHEMBL3976573 | 0.57 | HDAC4 (0.61) | PTPN1HDAC4HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192921-A2 | ABIETANES AND METHODS OF MAKING AND USING THE SAME | THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INCORPORATED (US) | 2023-10-05 | — | — | WO | disclosed |