Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 2/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30267096 | 0.77 | KDM1A (0.34) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL8893531 | 0.76 | DRD1 (0.45) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL202264 | 0.71 | TSHR (0.44) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| Methane SCHEMBL5909544 | 0.69 | SIGMAR1 (0.43) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| Lithium SCHEMBL7545662 | 0.69 | SIGMAR1 (0.43) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| Potassium SCHEMBL7551769 | 0.69 | SIGMAR1 (0.43) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL11772501 | 0.68 | ADRA2A (0.38) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL11772425 | 0.67 | CHRM2 (0.37) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL11772497 | 0.67 | HTR2A (0.38) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL11771917 | 0.67 | CHRM2 (0.37) | CHRM2HTR1AADRA2ACHRM1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107000124-A | Method for manufacturing optical film | 日本瑞翁株式会社 | 2017-08-01 | — | — | CN | disclosed |
| EP-1120389-B1 | Preparation process of fluorenes | JFE CHEMICAL CORP (JP) | 2003-11-26 | — | — | EP | disclosed |
| US-6344585-B2 | DEHYDROGENATION OF THE CORRESPONDING TETRAHYDROFLUORENECOMPOUND | ADCHEMCO CORPORATION (JP) | 2002-02-05 | — | — | US | disclosed |
| US-20010011144-A1 | Preparation process of fluorenes | ADCHEMCO CORPORATION (JP) | 2001-08-02 | — | — | US | disclosed |
| EP-1120389-A1 | Preparation process of fluorenes | Adchemco Corporation (JP) | 2001-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010011144-A1 | Preparation process of fluorenes | AFF1, NAF1, RER1 | CHRM2 2866/4885HTR1A 270/4885ADRA2A 1998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.