SCHEMBL2608797

SCHEMBL2608797

COc1ccc2ccc(CO)cc2c1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.44
NPC1 O15118 1/20 0.41
POLB P06746 1/20 0.41
RAB9A P51151 1/20 0.41
CA2 P00918 1/20 0.40
ACHE P22303 1/20 0.40
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
PDE4A P27815 1/20 0.39
PDE4B Q07343 1/20 0.39
PDE4C Q08493 1/20 0.39
PDE4D Q08499 1/20 0.39
TTR P02766 1/20 0.39
CYP4F2 P78329 1/20 0.38
CYP4A11 Q02928 1/20 0.38
MAPT P10636 1/20 0.38
PLAU P00749 1/20 0.38
HTT P42858 1/20 0.37
GAA P10253 2/20 0.37
FYN P06241 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7773470 0.84 MAPT (0.52) DHFRNPC1POLBRAB9ACA2
SCHEMBL19087103 0.78 CETP (0.55) CA2KMT2AMEN1MAPTGAA
SCHEMBL13176613 0.77 ESR1 (0.43) CA2TTRMAPTPLAUGAA
SCHEMBL7629184 0.76 MAPT (0.50) DHFRNPC1POLBRAB9ACA2
SCHEMBL12657996 0.76 ACHE (0.56) POLBACHEKMT2AMEN1MAPT
SCHEMBL3022833 0.76 CRHBP (0.50) DHFRNPC1POLBRAB9ACA2
SCHEMBL29997296 0.75 CA2 (0.68) NPC1POLBRAB9ACA2ACHE
SCHEMBL119395 0.75 CA2 (0.68) NPC1POLBRAB9ACA2ACHE
SCHEMBL28170408 0.75 CA2 (0.68) NPC1POLBRAB9ACA2ACHE
SCHEMBL2908419 0.75 MAOA (0.49) POLBKMT2AMEN1PDE4APDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9217053-B2 Active ester resin, thermosetting resin composition, cured product of same, semiconductor encapsulation material, prepreg, circuit board, and build-up film DIC CORPORATION (JP) 2015-12-22 US disclosed
US-20150118499-A1 ACTIVE ESTER RESIN, THERMOSETTING RESIN COMPOSITION, CURED PRODUCT OF SAME, SEMICONDUCTOR ENCAPSULATION MATERIAL, PREPREG, CIRCUIT BOARD, AND BUILD-UP FILM DIC CORPORATION (JP) 2015-04-30 US disclosed
US-8288003-B2 Method for producing phosphorus-containing phenolic compound, novel phosphorus-containing phenol, curable resin composition, cured product of the same, printed wiring board, and semiconductor sealing material DIC CORPORATION (JP) 2012-10-16 US disclosed
US-8263714-B2 Epoxy resin composition, cured article thereof, semiconductor sealing material, novel phenol resin, novel epoxy resin, method for producing novel phenol resin, and method for producing novel epoxy resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2012-09-11 US disclosed
US-8263714-B2 Epoxy resin composition, cured article thereof, semiconductor sealing material, novel phenol resin, novel epoxy resin, method for producing novel phenol resin, and method for producing novel epoxy resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2012-09-11 US disclosed
US-20120095156-A1 METHOD FOR PRODUCING PHOSPHORUS-CONTAINING PHENOLIC COMPOUND, NOVEL PHOSPHORUS-CONTAINING PHENOL, CURABLE RESIN COMPOSITION, CURED PRODUCT OF THE SAME, PRINTED WIRING BOARD, AND SEMICONDUCTOR SEALING MATERIAL DIC CORPORATION (JP) 2012-04-19 US disclosed
US-20110275739-A1 EPOXY RESIN COMPOSITION, CURED ARTICLE THEREOF, SEMICONDUCTOR SEALING MATERIAL, NOVEL PHENOL RESIN, NOVEL EPOXY RESIN, METHOD FOR PRODUCING NOVEL PHENOL RESIN, AND METHOD FOR PRODUCING NOVEL EPOXY RESIN DAINIPPON INK AND CHEMICALS, INC. (JP) 2011-11-10 US disclosed
US-20110275739-A1 EPOXY RESIN COMPOSITION, CURED ARTICLE THEREOF, SEMICONDUCTOR SEALING MATERIAL, NOVEL PHENOL RESIN, NOVEL EPOXY RESIN, METHOD FOR PRODUCING NOVEL PHENOL RESIN, AND METHOD FOR PRODUCING NOVEL EPOXY RESIN DAINIPPON INK AND CHEMICALS, INC. (JP) 2011-11-10 US disclosed
US-7985822-B2 Epoxy resin cured with phenol-formaldehyde resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2011-07-26 US disclosed
US-20100087590-A1 EPOXY RESIN COMPOSITION AND CURED ARTICLE THEREOF, SEMICONDUCTOR ENCAPSULATION MATERIAL, NOVEL PHENOL RESIN, AND NOVEL EPOXY RESIN DAINIPPON INK AND CHEMICALS, INC. (JP) 2010-04-08 US disclosed
US-20090054585-A1 EPOXY RESIN COMPOSITION AND CURED ARTICLE THEREOF, SEMICONDUCTOR ENCAPSULATION MATERIAL, NOVEL PHENOL RESIN, AND NOVEL EPOXY RESIN DAINIPPON INK AND CHEMICALS, INC. (JP) 2009-02-26 US disclosed
US-20080255315-A1 Epoxy Resin Composition,Cured Article Thereof, Semiconductor Sealing Material, Novel Phenol Resin, Novel Epoxy Resin,Method for Producing Novel Phenol Resin, And Method For Producing Novel Epoxy Resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2008-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120095156-A1 METHOD FOR PRODUCING PHOSPHORUS-CONTAINING PHENOLIC COMPOUND, NOVEL PHOSPHORUS-CONTAINING PHENOL, CURABLE RESIN COMPOSITION, CURED PRODUCT OF THE SAME, PRINTED WIRING BOARD, AND SEMICONDUCTOR SEALING MATERIAL PPA1, RBBP4, SMARCB1 DHFR 3648/4885NPC1 4638/4885POLB 151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.