SCHEMBL26088765

SCHEMBL26088765

CC(C(=O)N1CCN(c2ccc(F)cc2)c2cc(F)ccc21)N1CCCC1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC6A2 P23975 3/20 0.43
▸ SLC6A3 Q01959 3/20 0.43
▸ CHRNB2 P17787 2/20 0.43
▸ CHRNB4 P30926 2/20 0.43
▸ CHRNA3 P32297 2/20 0.43
▸ CHRNA4 P43681 2/20 0.43
▸ AVPR1A P37288 1/20 0.36
▸ KMT2A Q03164 2/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ LMNA P02545 2/20 0.36
▸ NOTUM Q6P988 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ SIGMAR1 Q99720 1/20 0.35
▸ NPC1 O15118 3/20 0.35
▸ KDM4E B2RXH2 3/20 0.35
▸ ALDH1A1 P00352 3/20 0.35
▸ MAPT P10636 3/20 0.35
▸ RAB9A P51151 2/20 0.35
▸ TSHR P16473 2/20 0.35
▸ TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26091655 0.99 SLC6A2 (0.45) SLC6A2SLC6A3CHRNB2CHRNB4CHRNA3
SCHEMBL26089204 0.93 CHRNB2 (0.44) SLC6A2SLC6A3CHRNB2CHRNB4CHRNA3
SCHEMBL26088697 0.92 CHRNB2 (0.46) SLC6A2SLC6A3CHRNB2CHRNB4CHRNA3
SCHEMBL26092300 0.91 SIGMAR1 (0.45) AVPR1AKMT2AMEN1LMNANOTUM
SCHEMBL26091668 0.90 AKR1C3 (0.39) AVPR1AKMT2AMEN1LMNASMN1; SMN2
SCHEMBL30379034 0.89 GAA (0.43) SLC6A2SLC6A3CHRNB2CHRNB4CHRNA3
SCHEMBL26091588 0.89 GAA (0.43) SLC6A2SLC6A3CHRNB2CHRNB4CHRNA3
SCHEMBL30378556 0.88 CHRNB2 (0.43) SLC6A2SLC6A3CHRNB2CHRNB4CHRNA3
SCHEMBL26090563 0.88 CHRNB2 (0.43) SLC6A2SLC6A3CHRNB2CHRNB4CHRNA3
SCHEMBL26088510 0.84 SIGMAR1 (0.44) AVPR1AKMT2AMEN1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250002464-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME SAPIENSBIO INC. (KR) 2025-01-02 — — US claimed
EP-4421070-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME Sapiensbio Inc. (KR) 2024-08-28 — — EP claimed
CN-118119612-A Novel compounds and pharmaceutical compositions comprising the same 萨皮恩斯生物有限公司 2024-05-31 — — CN claimed
WO-2023068755-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 주식회사 사피엔스바이오 2023-04-27 — — WO claimed
US-20250002464-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME SAPIENSBIO INC. (KR) 2025-01-02 — — US disclosed
EP-4421070-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME Sapiensbio Inc. (KR) 2024-08-28 — — EP disclosed
CN-118119612-A Novel compounds and pharmaceutical compositions comprising the same 萨皮恩斯生物有限公司 2024-05-31 — — CN disclosed
WO-2023068755-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 주식회사 사피엔스바이오 2023-04-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250002464-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME RHOA, ACTR2, MFAP1 SLC6A2 3367/4885SLC6A3 4500/4885CHRNB2 2641/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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