SCHEMBL26088697

SCHEMBL26088697

CC(C(=O)N1CCN(c2ccccc2)c2cc(F)ccc21)N1CCCCC1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CHRNB2 P17787 4/20 0.46
▸ SLC6A2 P23975 4/20 0.46
▸ CHRNB4 P30926 4/20 0.46
▸ CHRNA3 P32297 4/20 0.46
▸ CHRNA4 P43681 4/20 0.46
▸ SLC6A3 Q01959 4/20 0.46
▸ AVPR1A P37288 1/20 0.39
▸ ALDH1A1 P00352 5/20 0.39
▸ KDM4E B2RXH2 3/20 0.39
▸ GAA P10253 2/20 0.39
▸ LMNA P02545 2/20 0.38
▸ SMN1; SMN2 Q16637 2/20 0.38
▸ SIGMAR1 Q99720 2/20 0.38
▸ MAPT P10636 1/20 0.37
▸ TSHR P16473 1/20 0.37
▸ CHRNA1 P02708 3/20 0.37
▸ CHRNG P07510 3/20 0.37
▸ CHRNB1 P11230 3/20 0.37
▸ CHRND Q07001 3/20 0.37
▸ RAB9A P51151 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26089204 0.99 CHRNB2 (0.44) CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4
SCHEMBL26091655 0.93 SLC6A2 (0.45) CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4
SCHEMBL26088765 0.92 SLC6A2 (0.43) CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4
SCHEMBL26088510 0.90 SIGMAR1 (0.44) AVPR1AALDH1A1KDM4ELMNASMN1; SMN2
SCHEMBL26088865 0.89 ALDH1A1 (0.38) AVPR1AALDH1A1KDM4ELMNASMN1; SMN2
SCHEMBL26090563 0.87 CHRNB2 (0.43) CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4
SCHEMBL30378556 0.87 CHRNB2 (0.43) CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4
SCHEMBL30910050 0.87 GAA (0.46) CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4
SCHEMBL26088160 0.87 GAA (0.46) CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4
SCHEMBL30379034 0.86 GAA (0.43) CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250002464-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME SAPIENSBIO INC. (KR) 2025-01-02 — — US claimed
EP-4421070-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME Sapiensbio Inc. (KR) 2024-08-28 — — EP claimed
CN-118119612-A Novel compounds and pharmaceutical compositions comprising the same 萨皮恩斯生物有限公司 2024-05-31 — — CN claimed
WO-2023068755-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 주식회사 사피엔스바이오 2023-04-27 — — WO claimed
US-20250002464-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME SAPIENSBIO INC. (KR) 2025-01-02 — — US disclosed
EP-4421070-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME Sapiensbio Inc. (KR) 2024-08-28 — — EP disclosed
CN-118119612-A Novel compounds and pharmaceutical compositions comprising the same 萨皮恩斯生物有限公司 2024-05-31 — — CN disclosed
WO-2023068755-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 주식회사 사피엔스바이오 2023-04-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250002464-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME RHOA, ACTR2, MFAP1 CHRNB2 2641/4885SLC6A2 3367/4885CHRNB4 1986/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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