Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.58 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.58 |
| ▸ | ACHE | P22303 | 4/20 | 0.50 |
| ▸ | BCHE | P06276 | 4/20 | 0.50 |
| ▸ | BACE1 | P56817 | 3/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2614397 | 0.84 | ACHE (0.54) | PRMT5WDR77ACHEBCHEBACE1 | |
| SCHEMBL7276334 | 0.84 | ACHE (0.54) | PRMT5WDR77ACHEBCHEBACE1 | |
| SCHEMBL20008975 | 0.82 | ACHE (0.53) | PRMT5WDR77ACHEBCHEBACE1 | |
| SCHEMBL24652674 | 0.82 | NPC1 (0.58) | PRMT5WDR77ACHEBCHEBACE1 | |
| SCHEMBL3271398 | 0.80 | LTA4H (0.60) | ACHEBCHEBACE1SMN1; SMN2GAA | |
| SCHEMBL4512639 | 0.80 | LTA4H (0.60) | ACHEBCHEBACE1SMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL18038825 | 0.79 | LTA4H (0.58) | ACHEBCHEBACE1SMN1; SMN2GAA | |
| SCHEMBL11534247 | 0.78 | PRMT5 (0.50) | PRMT5WDR77ACHEBCHEBACE1 | |
| SCHEMBL11531230 | 0.78 | BCHE (0.52) | PRMT5WDR77ACHEBCHEBACE1 | |
| SCHEMBL14218548 | 0.77 | CYP1A2 (0.55) | PRMT5WDR77ACHEBCHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120101091-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101091-A1 | VIRAL POLYMERASE INHIBITORS | POLR2A, POLR2H, POLR2E | PRMT5 861/4885WDR77 2056/4885ACHE 3108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.