Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26089216 | 0.77 | ALDH1A1 (0.48) | ALDH1A1KDM4ELMNAKMT2ARECQL | |
| SCHEMBL26089094 | 0.73 | MAPT (0.44) | ALDH1A1KDM4ELMNAKMT2ATSHR | |
| SCHEMBL29284700 | 0.71 | ALDH1A1 (0.47) | ALDH1A1KDM4ELMNAKMT2ARECQL | |
| SCHEMBL26419161 | 0.71 | ALDH1A1 (0.47) | ALDH1A1KDM4ELMNAKMT2ARECQL | |
| SCHEMBL26088630 | 0.71 | ALDH1A1 (0.47) | ALDH1A1KDM4ELMNAKMT2ARECQL | |
| SCHEMBL26086567 | 0.70 | LMNA (0.44) | ALDH1A1KDM4ELMNAKMT2AMAPT | |
| SCHEMBL1399942 | 0.67 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNAKMT2ARECQL | |
| SCHEMBL1401174 | 0.67 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNAKMT2ARECQL | |
| SCHEMBL2498218 | 0.67 | ALDH1A1 (0.51) | ALDH1A1KDM4ELMNAKMT2ARECQL | |
| SCHEMBL4497673 | 0.67 | ALDH1A1 (0.57) | ALDH1A1KDM4ELMNAKMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12037322-B2 | AHR agonists | ELI LILLY AND COMPANY (US) | 2024-07-16 | — | — | US | disclosed |
| US-12037322-B2 | AHR agonists | ELI LILLY AND COMPANY (US) | 2024-07-16 | — | — | US | disclosed |
| US-20230127797-A1 | AHR AGONISTS | ELI LILLY AND COMPANY | 2023-04-27 | — | — | US | disclosed |
| US-20230127797-A1 | AHR AGONISTS | ELI LILLY AND COMPANY | 2023-04-27 | — | — | US | disclosed |
| US-20230127797-A1 | AHR AGONISTS | ELI LILLY AND COMPANY | 2023-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12037322-B2 | AHR agonists | AHR, ARNT, RORC | ALDH1A1 724/4885KDM4E 1656/4885LMNA 4176/4885 |
| US-20230127797-A1 | AHR AGONISTS | AHR, ARNT, RORC | ALDH1A1 724/4885KDM4E 1656/4885LMNA 4176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.