Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8710553 | 0.83 | NPSR1 (0.36) | NPSR1KDM4CALDH1A1KDM4EHSD17B10 | |
| SCHEMBL23930812 | 0.83 | NPSR1 (0.45) | NPSR1KDM4CALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7398766 | 0.73 | HPGD (0.37) | NPSR1KDM4CALDH1A1KDM4EMEN1 | |
| SCHEMBL8806965 | 0.73 | IGF1R (0.39) | — | |
| SCHEMBL9873189 | 0.71 | GPR84 (0.37) | ALDH1A1GAAMAPTLMNATSHR | |
| SCHEMBL8811268 | 0.69 | GPR84 (0.36) | ALDH1A1 | |
| SCHEMBL25244034 | 0.69 | KDM4E (0.41) | KDM4CALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL24283838 | 0.69 | LMNA (0.37) | NPSR1KDM4CALDH1A1HSD17B10HPGD | |
| SCHEMBL8809735 | 0.68 | GPR84 (0.41) | MAPT | |
| SCHEMBL23931077 | 0.68 | LMNA (0.35) | NPSR1KDM4CALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023069547-A1 | 5-MEMBERED HETEROARYL CARBOXAMIDE COMPOUNDS FOR TREATMENT OF HBV | ASSEMBLY BIOSCIENCES, INC. (US) | 2023-04-27 | — | — | WO | disclosed |