Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | USP1 | O94782 | 5/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26093218 | 0.90 | PTGS2 (0.40) | KDM4ESMN1; SMN2PTGS2PTGS1DGAT1 | |
| SCHEMBL26090304 | 0.82 | GRIN2B (0.36) | KDM4ESMN1; SMN2PTGS2PTGS1DGAT1 | |
| SCHEMBL30361043 | 0.82 | GRIN2B (0.36) | KDM4ESMN1; SMN2PTGS2PTGS1DGAT1 | |
| SCHEMBL26088968 | 0.80 | PTGS2 (0.37) | KDM4ESMN1; SMN2PTGS2GRIN2BRXRA | |
| SCHEMBL26093295 | 0.79 | ALDH1A1 (0.38) | KDM4ESMN1; SMN2PTGS2GRIN2BGRM5 | |
| SCHEMBL27348126 | 0.79 | DGAT1 (0.34) | KDM4ESMN1; SMN2PTGS2PTGS1DGAT1 | |
| SCHEMBL26093373 | 0.79 | DYRK1A (0.38) | GRIN2BGRIN1 | |
| SCHEMBL27348054 | 0.78 | PTGS2 (0.33) | KDM4EPTGS2PTGS1DGAT1USP1 | |
| SCHEMBL27348909 | 0.78 | PTGS2 (0.34) | PTGS2DGAT1 | |
| SCHEMBL27349031 | 0.77 | DGAT1 (0.33) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129053-A1 | HERBICIDAL IMIDAZOLE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-04-24 | — | — | US | disclosed |
| EP-4419517-A1 | HERBICIDAL IMIDAZOLE COMPOUNDS | Syngenta Crop Protection AG (CH) | 2024-08-28 | — | — | EP | disclosed |
| CN-118103362-A | Herbicidal imidazole compounds | 先正达农作物保护股份公司 | 2024-05-28 | — | — | CN | disclosed |
| WO-2023066783-A1 | HERBICIDAL IMIDAZOLE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-04-27 | — | — | WO | disclosed |
| WO-2023066783-A1 | HERBICIDAL IMIDAZOLE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250129053-A1 | HERBICIDAL IMIDAZOLE COMPOUNDS | DDT, H1-0, H1-3 | KDM4E 613/4885SMN1; SMN2 4587/4885PTGS2 1766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.