SCHEMBL27349031

SCHEMBL27349031

FC(F)(F)c1cn(Cc2ncc(Cl)cn2)c(-c2sc(Cl)nc2Cl)n1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27349028 0.83 DGAT1 (0.31) DGAT1
SCHEMBL27349014 0.80 P2RX7 (0.34) DGAT1
SCHEMBL27348054 0.80 PTGS2 (0.33) DGAT1
SCHEMBL27348909 0.80 PTGS2 (0.34) DGAT1
SCHEMBL27349024 0.78 DGAT1 (0.35) DGAT1
SCHEMBL27348126 0.78 DGAT1 (0.34) DGAT1
SCHEMBL26093218 0.77 PTGS2 (0.40) DGAT1
SCHEMBL26090152 0.77 KDM4E (0.46) DGAT1
SCHEMBL30361043 0.76 GRIN2B (0.36) DGAT1
SCHEMBL26090304 0.76 GRIN2B (0.36) DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023247358-A1 HERBICIDAL IMIDAZOLE-CONTAINING COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-12-28 WO disclosed