SCHEMBL26090156

SCHEMBL26090156

CSc1nc(NC(=O)C(N)C(C)O)c2ncn([C@]3(C(N)=O)O[C@H](CO)[C@@H](O)[C@H]3O)c2n1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ HTR2B P41595 2/20 0.35
▸ HTR2C P28335 1/20 0.35
▸ ADORA3 P0DMS8 2/20 0.33
▸ ADORA1 P30542 1/20 0.33
▸ ADRA2B P18089 1/20 0.32
▸ HTR2A P28223 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.32
▸ PKM P14618 1/20 0.32
▸ TARS1 P26639 2/20 0.32
▸ P2RY1 P47900 1/20 0.31
▸ P2RY12 Q9H244 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29413061 1.00 HTR2B (0.35) HTR2BHTR2CADORA3ADORA1ADRA2B
SCHEMBL16987222 0.86 TARS1 (0.38) ADORA1TARS1
SCHEMBL29435121 0.86 TARS1 (0.38) ADORA1TARS1
SCHEMBL28564130 0.86 TARS1 (0.38) ADORA1TARS1
SCHEMBL29238711 0.86 HTR2B (0.34) HTR2BHTR2CADORA3ADRA2BHTR2A
SCHEMBL29043762 0.85 KDM4E (0.31) HTR2BHTR2CKDM4EPKM
SCHEMBL29407144 0.85 KDM4E (0.31) HTR2BHTR2CKDM4EPKM
SCHEMBL31192291 0.81 HTR2C (0.31) HTR2BHTR2CKDM4EPKM
SCHEMBL28521252 0.81 HTR2C (0.31) HTR2BHTR2CKDM4EPKM
SCHEMBL28894185 0.79 ADORA3 (0.54) ADORA3ADORA1KDM4EPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119421870-A Lipid compound and application thereof 传信生物医药(苏州)有限公司 2025-02-11 — — CN claimed
CN-119384273-A Organ-specific delivery compositions for nucleic acids 传信生物医药(苏州)有限公司 2025-01-28 — — CN claimed
CN-117866948-B Negative selection method and system for purifying circular nucleic acid 上海环码生物医药有限公司 2024-12-13 — — CN claimed
CN-118660973-A RNA and DNA analysis Using engineered surfaces 阿丽达生物科学公司 2024-09-17 — — CN claimed
CN-118613500-A Modified mRNA treatment 沙塔克实验室有限公司 2024-09-06 — — CN claimed
CN-118475599-A Chimeric proteins for the treatment of skin inflammation 沙塔克实验室有限公司 2024-08-09 — — CN claimed
CN-117500823-A Chimeric proteins in autoimmunity 沙塔克实验室有限公司 2024-02-02 — — CN claimed
CN-117413065-A Constructs, methods and uses for the preparation of circular RNAs 上海环码生物医药有限公司 2024-01-16 — — CN claimed
CN-111744019-B Mannose-based mRNA targeted delivery system and application thereof 深圳瑞吉生物科技有限公司 2023-08-04 — — CN claimed
CN-114502204-A RNA combinations and compositions with reduced immunostimulatory properties 库尔维科公司 2022-05-13 — — CN claimed
CN-112390871-A In vivo production of proteins 现代泰克斯公司 2021-02-23 — — CN claimed
CN-113396219-B Purification of mRNA by tangential flow filtration ETHRIS GMBH (DE) 2026-05-26 — — CN disclosed
CN-122074087-A Reverse transcription mediated gene editing system and use thereof 阿伯生物技术公司 2026-05-22 — — CN disclosed
CN-122038302-A Modified T cells and methods of making and using the same 哈佛学院校长同事会 2026-05-15 — — CN disclosed
CN-122029278-A Constructs, methods and uses for the preparation of circular RNAs 上海环码生物医药有限公司 2026-05-12 — — CN disclosed
CN-110891553-A Method for producing liposome encapsulating RNA 葛兰素史密丝克莱恩生物有限公司 2020-03-17 — — CN disclosed
CN-110799644-A CBLB endonuclease variants, compositions, and methods of use 蓝鸟生物公司 2020-02-14 — — CN disclosed
CN-110582304-A RNA for treating or preventing liver disease 库尔维科公司 2019-12-17 — — CN disclosed
CN-110505877-A RNA cancer vaccine MODERNATX INC 2019-11-26 — — CN disclosed
CN-105308183-A Compositions and methods of altering cholesterol levels modeRNA Therapeutics 2016-02-03 — — CN disclosed
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